Embryo Selection for Cognitive Enhancement: Curiosity or Game-Changer?
On the genetic architecture of intelligence and other quantitative traits
Genome-Wide Complex Trait Analysis
Embryo editing for intelligence
Enabling large-scale genome editing by reducing DNA nicking
The Genome Project-Write
Technology Forecasting: The Garden of Forking Paths
Genetic Influences on the Behavior of Chickens Associated with Welfare and Productivity § Selection Involving Production Traits
We Are As Gods And Have To Get Good At It: Stewart Brand Talks About His Ecopragmatist Manifesto
2013-aa.pdf
Embryo Biopsies for Genomic Selection
Aurea Smigrodzki: The First Baby in History to Be Conceived With the Help of Polygenic Testing
The Financial Perks of Being Tall: An Extra Inch Correlates With an Estimated $800 in Increased Annual Earnings
Rare and Low-Frequency Coding Variants Alter Human Adult Height
Meta-analysis of genome-wide association studies for height and body mass index in ∼700,000 individuals of European ancestry
Accurate Genomic Prediction Of Human Height
Modeling functional enrichment improves polygenic prediction accuracy in UK Biobank and 23andMe data sets
CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits
The Evolutionary Genetics of Personality
The Evolutionary Genetics of Personality Revisited
The ‘Genius Babies’ Grow Up: What Happened to 15 Children from the Nobel Prize Sperm Bank?
Screening Human Embryos for Polygenic Traits Has Limited Utility
Calculator for the Potential Benefit of Embryo Selection Experiments Using Polygenic Risk Scores
Screening Human Embryos for Polygenic Traits Has Limited Utility [Supplement]
Utility of polygenic embryo screening for disease depends on the selection strategy
Problems with Using Polygenic Scores to Select Embryos
Utility and First Clinical Application of Screening Embryos for Polygenic Disease Risk Reduction
Preimplantation Genetic Testing for Polygenic Disease Relative Risk Reduction: Evaluation of Genomic Index Performance in 11,883 Adult Sibling Pairs
Embryo Screening for Polygenic Disease Risk: Recent Advances and Ethical Considerations
Sibling validation of polygenic risk scores and complex trait prediction
IQ, Academic Performance, Environment and Earnings
The Role of Premarket Factors in Black-White Wage Differences
1997-cawley.pdf
Copenhagen Consensus—Challenges and Opportunities: Hunger and Malnutrition
The Determinants of Individual Earnings: Skills, Preferences, and Schooling
Economic gains resulting from the reduction in children’s exposure to lead in the United States
Long-Run Economic Effects of Early Childhood Programs on Adult Earnings
CPI Inflation Calculator
Cognitive Enhancement and Network Effects: how Individual Prosperity Depends on Group Traits
‘IQ & SES’ directory
Vulnerability of children and the developing brain to neurotoxic hazards
2003-gottfredson.pdf
Why g matters: The complexity of everyday life
Childhood forecasting of a small segment of the population with large economic burden
2015-krapohl.pdf
Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (n = 112,151) and 24 GWAS consortia
Molecular genetic contributions to social deprivation and household income in UK Biobank (n = 112,151)
Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income
2016-hill-ses-health-geneticcorrelations.jpg
Polygenic risk scores applied to a single cohort reveal pleiotropy among hundreds of human phenotypes
A global overview of pleiotropy and genetic architecture in complex traits
Genome-wide association studies establish that human intelligence is highly heritable and polygenic
Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
Genomic analysis of family data reveals additional genetic effects on intelligence and personality
Impact of Measurement Error on Testing Genetic Association with Quantitative Traits
Statistical properties of simple random-effects models for genetic heritability
https://www.nature.com/mp/journal/v16/n10/extref/mp201185x1.doc
Most reported genetic associations with general intelligence are probably false positives
Intelligence [review]
Common DNA markers can account for more than half of the genetic influence on cognitive abilities
Childhood intelligence is heritable, highly polygenic and associated with FNBP1L
http://www.tweelingenregister.org/fileadmin/user_upload/publicaties/verslaggeving/NTR-publicaties_2014/Benyamin_MP_2014_sup.pdf
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Http://www.science.sciencemag.org/highwire/filestream/594571/field_highwire_adjunct_files/1/Rietveld.SM.revision.2.pdf
Molecular Genetic Contributions to Socioeconomic Status and Intelligence
Results of a ‘GWAS Plus:’ General Cognitive Ability Is Substantially Heritable and Massively Polygenic
2013-trzaskowski.pdf
Genetic influence on family socioeconomic status and children’s intelligence
Genomic architecture of human neuroanatomical diversity
https://neuroanatomy.github.io/pdfs/2014Toro-Bourgeron;GenomicArchitecture;Supplement.pdf
https://www.nature.com/articles/mp2014188
https://static-content.springer.com/esm/art%3A10.1038%2Fmp.2014.188/MediaObjects/41380_2015_BFmp2014188_MOESM469_ESM.pdf
A Genome-Wide Analysis of Putative Functional and Exonic Variation Associated With Extremely High Intelligence
https://www.aging-us.com/papers/v7/n12/full/100864.html
Genome-wide association study of cognitive functions and educational attainment in UK Biobank (n = 112 151)
https://www.nature.com/mp/journal/v21/n6/extref/mp201645x11.doc
The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
A genome-wide association study for extremely high intelligence
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Meta-Analysis of GREML Results from Multiple Cohorts
Meta-analysis of the heritability of human traits based on 50 years of twin studies
Phenome-wide Heritability Analysis of the UK Biobank
https://www.biorxiv.org/content/biorxiv/suppl/2016/08/18/070177.DC1/070177-1.xlsx
An atlas of genetic associations in UK Biobank
http://images.pearsonclinical.com/images/pdf/wisciv/WISCIVTechReport2.pdf
CRAN: Package Lmomco
Calculating The Gaussian Expected Maximum
gwern-orderstatistics-increasedvarianceadvantage-n100.png
gwern-orderstatistics-increasedvarianceadvantage-n1000.png
gwern-orderstatistics-increasedvarianceadvantage-n10000.png
https://gwern.shinyapps.io/orderStatisticsIncreasedVariance/
The Relationship Of Validity Coefficients To The Practical Effectiveness Of Tests In Selection: Discussion And Tables
Impact of valid selection procedures on work-force productivity
Seeing The Forest From The Trees: When Predicting The Behavior Or Status Of Groups, Correlate Means
What Does It Mean to Have a Low R2? A Warning about Misleading Interpretation
Calculating The Gaussian Expected Maximum § Probability of Bivariate Maximum
gwern-orderstatistics-maximums.png
Journal of Climate Volume 18 Issue 23 (2005)
Polygenic Influence on Educational Attainment: New Evidence from the National Longitudinal Study of Adolescent to Adult Health
https://www.science.org/doi/10.1126/science.1235488
Replicability and robustness of genome-wide-association studies for behavioral traits
https://media.nature.com/original/nature-assets/mp/journal/v19/n2/extref/mp2012184x1.doc
Common Genetic Variants Associated With Cognitive Performance Identified Using the Proxy-Phenotype Method
Proxy-Phenotype Method Identifies Common Genetic Variants Associated with Cognitive Performance
Polygenic Influence on Educational Attainment
Educational attainment-related loci identified by GWAS are associated with select personality traits and mathematics and language abilities
Genetic Variation Associated with Differential Educational Attainment in Adults Has Anticipated Associations with School Performance in Children
Polygenic Scores Associated With Educational Attainment in Adults Predict Educational Achievement and ADHD Symptoms in Children
Is the Effect of Parental Education on Offspring Biased or Moderated by Genotype?
https://journals.sagepub.com/doi/suppl/10.1177/2332858415599972/suppl_file/ERO599972_Online_Supplement.docx
Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT)
https://www.nature.com/mp/journal/v21/n11/extref/mp2015225x1.doc
https://www.nature.com/articles/mp201645/figures/2
GWAS for executive function and processing speed suggests involvement of the CADM2 gene
Genome-wide association study identifies 74 loci associated with educational attainment
https://media.nature.com/original/nature-assets/nature/journal/v533/n7604/extref/nature17671-s1.pdf
https://media.nature.com/original/nature-assets/nature/journal/v533/n7604/extref/nature17671-s2.xlsx
https://www.thessgac.org/data
https://www.nature.com/articles/mp2016107
https://media.nature.com/full/nature-assets/mp/journal/v22/n2/extref/mp2016107x1.pdf
A Polygenic Score for Higher Educational Attainment is Associated With Larger Brains
The nature of nurture: effects of parental genotypes
https://www.biorxiv.org/content/biorxiv/suppl/2017/11/14/219261.DC1/219261-1.pdf#page=2
Parent and Offspring Polygenic Scores As Predictors of Offspring Years of Education
Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence
The Nature of Nurture: Using a Virtual-Parent Design to Test Parenting Effects on Children’s Educational Attainment in Genotyped Families
https://www.nature.com/articles/s41398-018-0222-7
Multi-polygenic score approach to trait prediction
A combined analysis of genetically correlated traits identifies 107 loci associated with intelligence
Multi-trait analysis of genome-wide association summary statistics using MTAG
A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
Improving genetic prediction by leveraging genetic correlations among human diseases and traits
99 independent genetic loci influencing general cognitive function include genes associated with brain health and structure (n = 280,360)
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
https://static-content.springer.com/esm/art%3A10.1038%2Fs41588-018-0147-3/MediaObjects/41588_2018_147_MOESM1_ESM.pdf
The new genetics of intelligence
Genetic Endowments and Wealth Inequality
Genes, Education, and Labor Market Outcomes: Evidence from the Health and Retirement Study
Polygenic Score Analysis Of Educational Achievement And Intergenerational Mobility
Genomic prediction of cognitive traits in childhood and adolescence
Predicting educational achievement from genomic measures and socioeconomic status
Genetic ‘General Intelligence’, Objectively Determined and Measured
https://www.biorxiv.org/content/biorxiv/early/2019/09/12/766600.1/DC1/embed/media-1.xlsx
2019-delafuente-s7-geneticgpgses.png
Genetic Influence on Social Outcomes during and After the Soviet Era in Estonia
Educational attainment polygenic scores in Hungary: evidence for validity and a historical gene-environment interaction
Pathfinder: A gamified measure to integrate general cognitive ability into the biological, medical and behavioral sciences
Mixed model association for biobank-scale data sets
Better estimation of SNP heritability from summary statistics provides a new understanding of the genetic architecture of complex traits
Genomic SEM Provides Insights into the Multivariate Genetic Architecture of Complex Traits
Applying Compressed Sensing to Genome-Wide Association Studies
Determination of Nonlinear Genetic Architecture Using Compressed Sensing
Efficient Cross-Trait Penalized Regression Increases Prediction Accuracy in Large Cohorts Using Secondary Phenotypes
Improved genetic prediction of complex traits from individual-level data or summary statistics
A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts
Multi-scale Inference of Genetic Trait Architecture using Biologically Annotated Neural Networks
Making the most of Clumping and Thresholding for polygenic scores
Comments on Gwern’s ‘Embryo Selection for Intelligence’
Genome-Wide Association Study Results for Educational Attainment Aid in Identifying Genetic Heterogeneity of Schizophrenia
Reliability and validity of the UK Biobank cognitive tests
How Should We Critique Research?
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
LD Score regression as an estimator of confounding and genetic correlations in genome-wide association studies
The Genetics of Success: How Single-Nucleotide Polymorphisms Associated With Educational Attainment Relate to Life-Course Development
Statistical correction of the Winner’s Curse explains replication variability in quantitative trait genome-wide association studies
Statistical Methods in Genetics. 1951/2010
Estimating heritability without environmental bias
The Role of Parental Genotype in Predicting Offspring Years of Education: Evidence for Genetic Nurture
Genetic analysis of social-class mobility in five longitudinal studies
Comparing within-family and between-family polygenic score prediction
The Contribution of Cognitive and Noncognitive Skills to Intergenerational Social Mobility
Genetic Fortune: Winning or Losing Education, Income, and Health
Genome-wide association study of 1 million people identifies 111 loci for atrial fibrillation
Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets
Five years of GWAS discovery
10 Years of GWAS Discovery: Biology, Function, and Translation
The Fertility Clinic That Cut IVF Prices in Half: The Doctor in Charge Says He Opens the Door to More Families; Saying Yes to Patients Considered Too Old or Obese Elsewhere
Foreigners Come to Korea for Fertility Treatment
Korea Prepares Emergency Measures to Bolster Birthrate: Subsidies to Apply to All Households Seeking Infertility Treatment, Benefits to Expand for Paternal Leave
系统维护
China Travel
In China, An IVF Clinic Grapples With Huge Demand
China’s Bold Push into Genetically Customized Animals: New Kinds of Dogs, Goats and Monkeys Are Being Made Quickly, Although Scientists Voice Worries about Ethics and Whether the Methods Should Be Used on Humans
China Builds a Faster Beagle in Gene-Editing Race With U.S.
Simultaneous Editing of 3 Homoeoalleles in Hexaploid Bread Wheat Confers Heritable Resistance to Powdery Mildew
Monkeys Genetically Modified to Show Autism Symptoms: But It Is Unclear How Well the Results Match the Condition in Humans
Super-Muscly Pigs Created by Small Genetic Tweak: Researchers Hope the Genetically Engineered Animals Will Speed past Regulators
The Cost of Sequencing a Human Genome
https://www.genome.gov/pages/der/seqcost2015_4.xlsx
Whole Genome Sequencing Test
https://caglab.org/index.php/for-researchers/pricing-and-services.html
Microarray Analysis
404 Resource at '/content/dam/illumina-Marketing/documents/products/brochures/datasheet_omni_whole-Genome_arrays.pdf' Not Found: No Resource Found
Johns Hopkins University - 50x
https://www.ukbiobank.ac.uk/wp-content/uploads/2014/04/uk-biobank-axiom-array-content-summary-2014.pdf
https://www.rockefeller.edu/genomics/pricing/
Genotyping—UK Biobank Array on 500,000 Participants
https://www.ukbiobank.ac.uk/frontiers-meeting-london-2014
https://www.ukbiobank.ac.uk/wp-content/uploads/2011/03/2014-uk-biobank-limited-signed-2014-report-and-financial-statements.pdf
DNA Test Firm 23andMe Raises $250 Million to Make New Drugs
https://web.archive.org/web/20170607224420/https://nhsa.org/pr-update/nhsa-statement-fy-2018-president%E2%80%99s-budget
Genes for Good: Engaging the Public in Genetics Research via Social Media
The End of Insurance (Some of It)
2020-08-nhgri-sequencingcostpergenome.jpg
Genetic Screening Centers (PGD)
2010-turkaspa.pdf
https://geneticalliance.org.uk/information/services-and-testing/how-can-i-access-preimplantation-genetic-diagnosis/#Question6
https://web.archive.org/web/20160311150735/http://www.rhtp.org/fertility/pgd/
Preimplantation Genetic Diagnosis: It's No Walk in the Park
https://www.sdfertility.com/fertility-treatments/genetic-testing/pgd
PGD Costs
LifeView - PGT-P
‘leaky pipelines’ directory
Clinical outcome of preimplantation genetic diagnosis and screening using next generation sequencing
Cost-Effectiveness Analysis of Preimplantation Genetic Screening and in Vitro Fertilization versus Expectant Management in Patients With Unexplained Recurrent Pregnancy Loss
2012-hodeswertz.pdf
https://web.archive.org/web/20100706183112/http://www.resolve.org/family-building-options/insurance_coverage/the-costs-of-infertility-treatment.html
Technical Update: Preimplantation Genetic Diagnosis and Screening
https://academic.oup.com/humrep/article/26/7/1768/2913935
2011-sunkara-figure2-eggembryodistribution.jpg
Weight BMI and Fertility and IVF Success
https://www.cdc.gov/art/pdf/2013-report/art_2013_national_summary_report.pdf
Tryon’s Rat Experiment
1940-tryon-figure4-mazebrightdullrats-distributions.png
Genetic Differences in Maze-Learning Ability in Rats (XIII)
2019-coop-illinoislongtermselectionexperiment-responsetoselection.jpg
2019-coop-illinoislongtermselectionexperiment-responsetoselection-animation.mp4
Genomic characterization of world’s longest selection experiment in mouse reveals the complexity of polygenic traits
1926-cox-theearlymentaltraitsof300geniuses.pdf
SMPY Bibliography
When Lightning Strikes Twice
‘Anne Roe’s Scientists’ directory
https://www.cdc.gov/nchs/births.htm
Trends over 15 Years in ART in Europe: an Analysis of 6 Million Cycles
2017-calhazjorge.pdf
Resultaterne for 2018 Er Baseret På Indberetninger Fra Offentlige Såvel Som Private Fertilitetsklinikker Til Sundhedsdatastyrelsens IVF Register (SEI)...For Patienter Med Bopæl I Danmark Forventes 6.019 Børn Født, Svarende Til Ca. 9.8% Af En Fødselsårgang (2018:61.476 Børn Født I Danmark).
Assisted Reproductive Technology in Australia and New Zealand 2018 § Pg7
Australia’s Birth Rate Lowest on Record, but More Babies Than Ever
Births and Deaths: Year Ended December 2018
IVF Accounts for 5% of Babies Born in Japan in 2015: Survey
https://sundhedsdatastyrelsen.dk/da/404/?item=%2fda%2ftal-og-analyser%2fanalyser-og-rapporter%2fandre-analyser-og-rapporter%2fassisteret-reproduktion&user=extranet%5cAnonymous&site=sds
The Longer-Term Health Outcomes for Children Born As a Result of IVF Treatment. Part II—Mental Health and Development Outcomes
Human Accomplishment
Why Eugenics Won't Come Back
The Moral Maze of Using a Dead Man’s Sperm
What women want in their sperm donor: A study of more than 1,000 women’s sperm donor selections
Quantitative Genetics in the Postmodern Family of the Donor Sibling Registry
2012-choi.pdf
4310660 192..195
2005-liao.pdf
2008-scotet.pdf
10897_2015_9833_Article 987..1000
2006-sawyer.pdf
Newborn Screening Showing Decreasing Incidence of Cystic Fibrosis
Influence of five years of antenatal screening on the paediatric cystic fibrosis population in one region
Population-based carrier screening for cystic fibrosis in Victoria: The first 3 years experience
Clinical Utility of Expanded Carrier Screening: Reproductive Behaviors of At-Risk Couples
Expanded Carrier Screening in an Infertile Population: How Often Is Clinical Decision Making Affected?
Prenatal testing in Huntington disease: after the test, choices recommence
We Don’t Want to Know What Will Kill Us: Years of data on genetic testing reveal that when given the option, most people want less information, not more
When Quality Beats Quantity: Decision Theory, Drug Discovery, and the Reproducibility Crisis
Women May Have an Alternative to Freezing Their Eggs
Engineering the Perfect Baby: Scientists Are Developing Ways to Edit the DNA of Tomorrow‘s Children. Should They Stop Before It’s Too Late?
https://web.archive.org/web/20160307210322/http://www2.technologyreview.com/news/427672/egg-stem-cells/
Why Tool AIs Want to Be Agent AIs
Optimal Selection Based On Relative Rank (The ‘Secretary Problem’)
Introduction to Quantitative Genetics
Chapter 21: Correlations Between Characters
The Reversal Test: Eliminating Status Quo Bias in Applied Ethics
Theory of Index Selection
Applications of Index Selection
UK Biobank
The Efficiency of 3 Methods of Selection
Animal Breeding Plans, Lush 1943: How Selection Changes A Population, ‘Selection For Many Characteristics At Once’
Contrasting the genetic architecture of 30 complex traits from summary association data
GBD Compare
Height, Body Mass Index, and Socioeconomic Status: Mendelian Randomization Study in UK Biobank
Genetic studies of body mass index yield new insights for obesity biology
Assessing the genetic overlap between BMI and cognitive function
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Population trends and variation in body mass index 1971–2008 in the Framingham Heart Study Offspring Cohort
The Marginal External Cost of Obesity in the United States
Genetic Predisposition to Obesity and Medicare Expenditures
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442244/bin/NIHMS393294-supplement-2.pdf
Schizophrenia and Children and Offspring
The Lifetime Cost of Diabetes and Its Implications for Diabetes Prevention
Lifetime Risk for Diabetes Mellitus in the United States
High Loading of Polygenic Risk for ADHD in Children With Comorbid Aggression
Shared Genetic Influences Between Attention-Deficit/Hyperactivity Disorder (ADHD) Traits in Children and Clinical ADHD
Attention-Deficit/Hyperactivity Disorder Polygenic Risk Scores Predict Attention Problems in a Population-Based Sample of Children
Shared polygenic contribution between childhood attention-deficit hyperactivity disorder and adult schizophrenia
The Relative Contribution of Common and Rare Genetic Variants to ADHD
The effects of attention-deficit/hyperactivity disorder on employment and household income
Polygenic risk scores for schizophrenia and bipolar disorder predict creativity
Common Polygenic Variation Contributes to Risk of Schizophrenia and Bipolar Disorder
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
Large-Scale Genome-Wide Association Analysis of Bipolar Disorder Identifies a New Susceptibility Locus near ODZ4: Supplement 1
Genome-wide association study of over 40,000 bipolar disorder cases provides novel biological insights
A126_jun05Hirschfeld_S85toS90
An economic evaluation of manic-depressive illness—1991
2015-agerbo.pdf
Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms
Biological insights from 108 schizophrenia-associated genetic loci
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia
The Global Costs of Schizophrenia
The Economic Burden of Schizophrenia in the United States in 2002
Years of Potential Life Lost and Life Expectancy in Schizophrenia: a Systematic Review and Meta-Analysis
Everything Is Correlated
https://ldsc.broadinstitute.org/
LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis
https://ldsc.broadinstitute.org/static/media/LD-Hub_genetic_correlation_49x49.xlsx
https://ldsc.broadinstitute.org/static/media/LD-Hub_study_information_and_SNP_heritability.xlsx
Application of Linear Mixed Models to Study Genetic Stability of Height and Body Mass Index across Countries and Time
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
Physical and neurobehavioral determinants of reproductive onset and success
The Long-Term Risks of Early Puberty
Common polygenic variation enhances risk prediction for Alzheimer’s disease
The burden of health care costs for patients with dementia in the last 5 years of life
A genome-wide association study of anorexia nervosa
Identification of risk loci with shared effects on 5 major psychiatric disorders: a genome-wide analysis
Fourteen Economic Facts on Education and Economic Opportunity
Large-scale association analysis identifies new risk loci for coronary artery disease
2003-birnbaum.pdf
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Appendix II: Cost Savings from Curing Crohn's Disease (CD)
A Mega-Analysis of Genome-Wide Association Studies for Major Depressive Disorder
Identification of 15 genetic loci associated with risk of major depression in individuals of European descent
Long-term economic costs of psychological problems during childhood
Tobacco Use Among Adults --- United States, 2005
Polygenic risk scores for smoking: predictors for alcohol and cannabis use?
The lifetime risk of adult-onset rheumatoid arthritis and other inflammatory autoimmune rheumatic diseases
Genetics of rheumatoid arthritis contributes to biology and drug discovery
Economic Burden of Rheumatoid Arthritis: a Systematic Review
Systematic Review: the Costs of Ulcerative Colitis in Western Countries
2011-park.pdf
Epidemiology, demographic characteristics and prognostic predictors of ulcerative colitis
Intelligence and All-Cause Mortality in the 6-Day Sample of the Scottish Mental Survey 1947 and Their Siblings: Testing the Contribution of Family Background
Quantitative analysis of population-scale family trees with millions of relatives
Genomic underpinnings of lifespan allow prediction and reveal basis in modern risks
Why a Pro/con List Is 75% As Good As Your Fancy Machine Learning Algorithm
https://web.archive.org/web/20210225235349/https://simplystatistics.org/2015/04/09/a-blessing-of-dimensionality-often-observed-in-high-dimensional-data-sets/
Procreative beneficence and in vitro gametogenesis
Methods for Strong Human Germline Engineering § Gamete Selection
Assessing human sperm morphology: top models, underdogs or biometrics?
Activation of Toll-like receptor 7 & 8 encoded by the X chromosome alters sperm motility and provides a novel simple technology for sexing sperm
Microfluidic-based sperm sorting & analysis for treatment of male infertility
Haploid selection in animals: Exploring the fitness consequences and underlying mechanisms
Intelligence and semen quality are positively correlated
Why is intelligence correlated with semen quality?: Biochemical pathways common to sperm and neuron function and their vulnerability to pleiotropic mutations
Good Semen Quality and Life Expectancy: A Cohort Study of 43,277 Men
Infertility etiologies are genetically and clinically linked with other diseases in single meta-diseases
Does Human Ejaculate Quality Relate to Phenotypic Traits?
No Evidence for a Relationship between Intelligence and Ejaculate Quality
Haploid Selection in ‘Diploid’ Organisms
Insights about variation in meiosis from 31,228 human sperm genomes
Tinder for Sperm: Even in the Petri Dish, Looks and Athleticism Are Prized: What makes one sperm cell—a blob of DNA with a tail—stand out? The selection process is like a microscopic Mr. America contest
Advanced sperm selection techniques for assisted reproduction (Review)
Methods for Strong Human Germline Engineering § Chromosome Selection
https://www.reddit.com/r/slatestarcodex/comments/8p91kt/crazy_ideas_thread_part_ii/e0b6rzm/?context=3
Chromosome transplantation as a novel approach for correcting complex genomic disorders
Unleashing meiotic crossovers in crops
2008-wijnker.pdf
Assessing by modeling the consequences of increased recombination in genomic selection of Oryza sativa and Brassica rapa
Chapter 14. Short-term Changes in the Mean: 2. Truncation and Threshold Selection [2013 draft]
Fecundity of Patients With Schizophrenia, Autism, Bipolar Disorder, Depression, Anorexia Nervosa, or Substance Abuse vs Their Unaffected Siblings
Evolutionary Perspectives on Genetic and Environmental Risk Factors for Psychiatric Disorders
Multi-Stage Bean Machine Visualization: Advantages of Repeated Optimization
Construction of arbitrarily strong amplifiers of natural selection using evolutionary graph theory
History of Iterated Embryo Selection
Strategies to Utilize Marker-Quantitative Trait Loci Associations
[Transclude the forward-link's
context]
In vitro eugenics
Frequently Asked Questions
In Vitro Gametogenesis: Just Another Way to Have a Baby?
Consensus Statement: Science Ethics and Policy Challenges of Pluripotent Stem Cell-Derived Gametes
Stem Cells: Egg Engineers
Potential Genetic Improvement of Cattle by Fertilization of Fetal Oocytes in Vitro
In Vitro Breeding: Application of Embryonic Stem Cells to Animal Production
Gametes from stem cells: Status and applications in animal reproduction
Artificially produced gametes in mice, humans and other species
Revolutionize Livestock Breeding in the Future: an Animal Embryo-Stem Cell Breeding System in a Dish
Perspectives of germ cell development in vitro in mammals
SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate
Complete Meiosis from Embryonic Stem Cell-Derived Germ Cells In Vitro
Reconstitution in Vitro of the Entire Cycle of the Mouse Female Germ Line
MLL1 Inhibition Reprograms Epiblast Stem Cells to Naive Pluripotency
https://www.pnas.org/doi/10.1073/pnas.1716161115
Functional Oocytes Derived from Granulosa Cells
Generation of ovarian follicles from mouse pluripotent stem cells
Controlled modeling of human epiblast and amnion development using stem cells
How to (Really) Engineer a Human Baby: A Global Meeting in Washington, D.C., Isn‘t Just about Whether or Not We Should Alter Our Species With CRISPR. It’s about How We Can Pull It Off.
Historical Progression of Racing Performance in Thoroughbreds and Man
Effects of periodic bottlenecks on the dynamics of adaptive evolution in microbial populations
When You Hear the Margin of Error Is Plus or Minus 3 Percent, Think 7 Instead
A Theory of Limits in Natural Selection
https://web.archive.org/web/20220301025405/http://nitro.biosci.arizona.edu/zbook/NewVolume_2/pdf/Chapter26.pdf
http://nitro.biosci.arizona.edu/workshops/Aarhus2006/pdfs/WalshLT.pdf
Genetic Studies on the Protein Content of Maize
The Result of Selecting Fluctuating Variations: Data from the Illinois Corn Breeding Experiments
Large Genetic Change at Small Fitness Cost in Large Populations of Drosophila melanogaster Selected for Wind Tunnel Flight: Rethinking Fitness Surfaces
Population Size and Long-Term Selection
2018-walsh-c26-weberfruitflyselectivebreeding.jpg
Use of haplotypes to estimate Mendelian sampling effects and selection limits
Selection on Net Merit to Improve Lifetime Profit
Genomic Selection in Dairy Cattle: The USDA Experience
2011-cole-selectionlimits-figure5-perchromosome.jpg
On epistasis: why it is unimportant in polygenic directional selection
Nature Still Battles Nurture in the Haunting World of Social Genomics: Nathaniel Comfort Lauds a Sociologist's Study of the Problems Built into Genetic Research
Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model
Genetic Architecture of Complex Traits and Disease Risk Predictors
Common DNA Variants Accurately Rank an Individual of Extreme Height
Evolution By Selection: The Implications of Winter’s Selection Experiment
The Mean and Variability As Affected by Continuous Selection for Composition in Corn
Seventy Generations of Selection for Oil and Protein in Maize
Number of Mendelian Factors in Quantitative Inheritance
Student
1930-fisher-thegeneticaltheoryofnaturalselection.pdf#page=119
https://ssgac.org/documents/CHIC_Summary_Benyamin2014.txt.gz
https://ssgac.org/documents/CHIC_Benyamin2014_Summary_Notes.pdf
https://www.broadinstitute.org/snap/snap
The Clones of Polo—Adolfo Cambiaso Interview
Dog Cloning For Special Forces: Breed All You Can Breed
‘Bayes/regression-to-mean’ directory
clone#liability-threshold-model
[Transclude the forward-link's
context]
A theory of limits in artificial selection
Rates of Change in Quantitative Traits from Fixation of New Mutations
Increased selection response in larger populations. II. Selection for ethanol vapor resistance in Drosophila melanogaster at two population sizes
Genetic Analysis of a ‘Plateaued’ Population of Drosophila Melanogaster
The Limits to Artificial Selection for Body Weight in the Mouse II. The Genetic Nature of the Limits
Long-term selection for a quantitative character in large replicate populations of Drosophila melanogaster: Part 3: The nature of residual genetic variability
Attenuation of Genetic Progress under Continued Selection in Poultry
Studies on Natural Populations of Drosophila. II. Heritability and Response to Selection for Wing Length in Drosophila Melanogaster and D. Simulans at Different Temperatures
1971-wilson.pdf
1963-sheldon.pdf
An Experimental Check on Quantitative Genetical Theory II. The Long-Term Effects of Selection
Evaluating Methods of Updating Training Data in Long-Term Genomewide Selection
Evolution of the Human Brain: From Matter to Mind
On Evolution § Pg82
Iodine and Adult IQ meta-analysis
Genius Revisited Revisited
Society Is Fixed, Biology Is Mutable
Xenopsychology
The Hollow Men II: Some Reflections on Westminster and Whitehall Dysfunction
Selection against variants in the genome associated with educational attainment
https://www.amazon.com/Genetics-Human-Populations-L-Cavalli-Sforza/dp/0486406938
1994-charlesworth-evolutioninagestructuredpopulations.pdf
SOME CHANGES IN SOCIAL LIFE IN A COMMUNITY WITH A FALLING INTELLIGENCE QUOTIENT
The Ties That Bind: Implicit Contracts and Management Practices in Family-Run Firms
Intellectual Brilliance and Presidential Performance: Why Pure Intelligence (Or Openness) Doesn't Suffice
What Botswana Can Teach Us About Political Stability
https://galton.org/books/hereditary-genius/text/pdf/galton-1869-genius-v3.pdf#page=162
A Listing of Extinct British Peerages
The Mind And Society Vol III
Smallpox on the Steppe
Queens of Infamy: The Rise of Catherine De‘ Medici; Kings and Popes Thought She Was Their Pawn. The Merchant’s Daughter Begged to Differ
IMDb: The F***ing Fulfords (2004): Quotes: Francis Fulford
The Life-Spans of Empires
The Ottoman Empire: Succession, Deposition and Fratricide: Getting and Keeping the Throne in the Ottoman Empire Was No Easy Task. For a New Sultan, the Most Foolproof Method of Securing Power Was to Kill All Other Claimants
Are CEOs Born Leaders? Lessons from Traits of a Million Individuals
Selectiongain: an R Package for Optimizing Multi-Stage Selection
John Von Neumann (1903–1957)
A New Method of Trace DNA Testing Could Solve More Shootings
Framed for Murder By His Own DNA: We Leave Traces of Our Genetic Material Everywhere, Even on Things We’ve Never Touched. That Got Lukis Anderson Charged With a Brutal Crime He Didn’t Commit.
Can DNA Evidence Solve a 30-Year-Old Crime? San Diego Police Believe They‘Ve Finally Cracked the Case of a 14-Year-Old Girl Murdered in 1984. But What If They’re Wrong?
‘(S) Reporting And Collection Needs: Paraguay’, 2008
‘(S) Reporting And Collection Needs: African Great Lakes (Droc, Burundi, Rwanda)’, 2009
Hacking the President’s DNA
Natural History Museums Are Teeming With Undiscovered Species: Tracking Them down Is a Globe-Trotting Adventure That Rivals Any Jungle Expedition
Genomics reveals the origins of ancient specimens
Using historical museum samples to examine divergent and parallel evolution in the invasive starling
Is DNA Left on Envelopes Fair Game for Testing? The Genealogist‘s Dream of Testing Old, Spit-Laced Artifacts Is Coming True—But Raising Questions about Who Controls Dead People’s DNA
German fighter pilot identified after 79 years from DNA on envelope
Ancient DNA from Mastics Solidifies Connection between Material Culture and Genetics of Mesolithic Hunter--Gatherers in Scandinavia
A 5700 year-old human genome and oral microbiome from chewed birch pitch
Urine as a high-quality source of host genomic DNA from wild populations
The York Gospels: a 1,000-Year Biological Palimpsest
Metagenomic analysis of a blood stain from the French revolutionary Jean-Paul Marat (1743–1793)
Identifying a Living Great-Grandson of the Lakota Sioux Leader Tatanka Iyotake (Sitting Bull)
Somerton man mystery solved as DNA points to man’s identity, professor claims
Genome-scale sequencing and analysis of human, wolf and bison DNA from 25,000 year-old sediment
Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments
Italian Scientists ‘Recreate DNA’ of Fascist Warrior-Poet from Semen Stains: Forensic Team Says It Used Handkerchief Splashed With Gabriele D’Annunzio’s Sperm to Recreate Eccentric, 19th-Century, Rightwing Leader’s Genetic Blueprint
https://familytreewebinars.com/uploads/video_vtt/MHLive-GiladJaphet1.vtt
Gilad's Keynote Address - MyHeritage LIVE - November 2018
‘emergenesis’ directory
https://www.rrauction.com/past_auction_results.cfm?SearchCrit=albert%20einstein&order=LP&oper=exact&scope=titleonly
https://www.rrauction.com/auctions/lot-detail/31909050347196/
Intellectuals
Scientists and Inventors
https://www.rrauction.com/auctions/lot-detail/339330505546026/
Olympic Memorabilia: All Auction Items
