- See Also
-
Links
- “Senolytic Effect of High Intensity Interval Exercise on Human Skeletal Muscle”, Et Al 2023
- “Senolytic Drugs, Dasatinib and Quercetin, Attenuate Adipose Tissue Inflammation, and Ameliorate Metabolic Function in Old Age”, Et Al 2023
- “SenMayo: A New Gene Set Identifies Senescent Cells and Predicts Senescence-associated Pathways across Tissues”, Et Al 2022
- “Unity Biotechnology Announces Positive Data in Phase 2 BEHOLD Study of UBX1325 in Patients With Diabetic Macular Edema”, 2022
- “Mitochondrial Dysfunction in Cell Senescence and Aging”, Et Al 2022
- “Orally-active, Clinically-translatable Senolytics Restore Α-Klotho in Mice and Humans”, Et Al 2022
- “Skin Senescence: Mechanisms and Impact on Whole-body Aging”, Et Al 2022
- “Restoration of Hippocampal Neural Precursor Function by Ablation of Senescent Cells in the Aging Stem Cell Niche”, Et Al 2022
- “Combination of Dasatinib and Quercetin Improves Cognitive Abilities in Aged Male Wistar Rats, Alleviates Inflammation and Changes Hippocampal Synaptic Plasticity and Histone H3 Methylation Profile”, Et Al 2022
- “Results of a 5-Year N-of-1 Growth Hormone Releasing Hormone Gene Therapy Experiment”, Et Al 2021
- “Deletion of SA Β-Gal+ Cells Using Senolytics Improves Muscle Regeneration in Old Mice”, Et Al 2021
- “A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues”, Et Al 2021
- “Senolytic Vaccination Improves Normal and Pathological Age-related Phenotypes and Increases Lifespan in Progeroid Mice”, Et Al 2021
- “The Flavonoid Procyanidin C1 Has Senotherapeutic Activity and Increases Lifespan in Mice”, Et Al 2021
- “Targeting P21Cip1 Highly Expressing Cells in Adipose Tissue Alleviates Insulin Resistance in Obesity”, Et Al 2021
- “Sexual Dimorphic Responses of C57BL/6 Mice to Fisetin or Dasatinib and Quercetin Cocktail Oral Treatment”, Et Al 2021
- “A Collective Analysis of Lifespan-extending Compounds in Diverse Model Organisms, and of Species Whose Lifespan Can Be Extended the Most by the Application of Compounds”, 2021
- “The Metabolic Roots of Senescence: Mechanisms and Opportunities for Intervention”, 2021
- “Strategies for Targeting Senescent Cells in Human Disease”, Et Al 2021
- “Modulation of Fracture Healing by the Transient Accumulation of Senescent Cells”, Et Al 2021
- “Fisetin for COVID-19 in Skilled Nursing Facilities: Senolytic Trials in the COVID Era”, Et Al 2021
- “Senolytics and the Compression of Late-life Mortality”, 2021
- “Procyanidin C1 Is a Natural Agent With Senolytic Activity against Aging and Age-related Diseases”, Et Al 2021
- “Oxylipin Biosynthesis Reinforces Cellular Senescence and Allows Detection of Senolysis”, Et Al 2021
- “Whole-body Senescent Cell Clearance Alleviates Age-related Brain Inflammation and Cognitive Impairment in Mice”, Et Al 2021
- “The Quest to Slow Ageing through Drug Discovery”, Et Al 2020
- “Senolytic Drugs: from Discovery to Translation”, 2020
- “A Look Back at 2019: Progress Towards the Treatment of Aging As a Medical Condition”, 2019
- “Senolytics Decrease Senescent Cells in Humans: Preliminary Report from a Clinical Trial of Dasatinib plus Quercetin in Individuals With Diabetic Kidney Disease”, Et Al 2019
- “Metformin and Aging: A Review”, 2019
- “Senolytic Treatment Targets Aberrant P21-expression to Restore Liver Regeneration in Adult Mice”, Et Al 2019
- “Galactose-modified Duocarmycin Prodrugs As Senolytics”, Et Al 2019
- “Senolytics Improve Physical Function and Increase Lifespan in Old Age”, Et Al 2018
- “Investigation of Quercetin and Hyperoside As Senolytics in Adult Human Endothelial Cells”, Et Al 2017
- “Targeting Cellular Senescence Prevents Age-related Bone Loss in Mice”, Et Al 2017
- “The Clinical Potential of Senolytic Drugs”, Et Al 2017
- “Naturally Occurring P16(Ink4a)-positive Cells Shorten Healthy Lifespan”, Et Al 2016
- Wikipedia
- Miscellaneous
- Link Bibliography
See Also
Links
“Senolytic Effect of High Intensity Interval Exercise on Human Skeletal Muscle”, Et Al 2023
“Senolytic effect of high intensity interval exercise on human skeletal muscle”, 2023-02-08 (; similar)
“Senolytic Drugs, Dasatinib and Quercetin, Attenuate Adipose Tissue Inflammation, and Ameliorate Metabolic Function in Old Age”, Et Al 2023
“Senolytic drugs, dasatinib and quercetin, attenuate adipose tissue inflammation, and ameliorate metabolic function in old age”, 2023-01-13 (similar)
“SenMayo: A New Gene Set Identifies Senescent Cells and Predicts Senescence-associated Pathways across Tissues”, Et Al 2022
“SenMayo: A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues”, 2022-08-16 (similar; bibliography)
“Unity Biotechnology Announces Positive Data in Phase 2 BEHOLD Study of UBX1325 in Patients With Diabetic Macular Edema”, 2022
“Unity Biotechnology Announces Positive Data in Phase 2 BEHOLD Study of UBX1325 in Patients with Diabetic Macular Edema”, 2022-08-12 (similar)
“Mitochondrial Dysfunction in Cell Senescence and Aging”, Et Al 2022
“Mitochondrial dysfunction in cell senescence and aging”, 2022-07-01 (similar)
“Orally-active, Clinically-translatable Senolytics Restore Α-Klotho in Mice and Humans”, Et Al 2022
“Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans”, 2022-03-13 (similar)
“Skin Senescence: Mechanisms and Impact on Whole-body Aging”, Et Al 2022
“Skin senescence: mechanisms and impact on whole-body aging”, 2022-02 (similar)
“Restoration of Hippocampal Neural Precursor Function by Ablation of Senescent Cells in the Aging Stem Cell Niche”, Et Al 2022
“Restoration of hippocampal neural precursor function by ablation of senescent cells in the aging stem cell niche”, 2022-01-20 (similar)
“Combination of Dasatinib and Quercetin Improves Cognitive Abilities in Aged Male Wistar Rats, Alleviates Inflammation and Changes Hippocampal Synaptic Plasticity and Histone H3 Methylation Profile”, Et Al 2022
“Combination of dasatinib and quercetin improves cognitive abilities in aged male Wistar rats, alleviates inflammation and changes hippocampal synaptic plasticity and histone H3 methylation profile”, 2022-01-18 (similar)
“Results of a 5-Year N-of-1 Growth Hormone Releasing Hormone Gene Therapy Experiment”, Et Al 2021
“Results of a 5-Year n-of-1 Growth Hormone Releasing Hormone Gene Therapy Experiment”, 2021-12-16 (; similar; bibliography)
“Deletion of SA Β-Gal+ Cells Using Senolytics Improves Muscle Regeneration in Old Mice”, Et Al 2021
“Deletion of SA β-Gal+ cells using senolytics improves muscle regeneration in old mice”, 2021-12-13 (; similar; bibliography)
“A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues”, Et Al 2021
“A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues”, 2021-12-11 (similar)
“Senolytic Vaccination Improves Normal and Pathological Age-related Phenotypes and Increases Lifespan in Progeroid Mice”, Et Al 2021
“Senolytic vaccination improves normal and pathological age-related phenotypes and increases lifespan in progeroid mice”, 2021-12-10 (similar; bibliography)
“The Flavonoid Procyanidin C1 Has Senotherapeutic Activity and Increases Lifespan in Mice”, Et Al 2021
“The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice”, 2021-12-06 (similar)
“Targeting P21Cip1 Highly Expressing Cells in Adipose Tissue Alleviates Insulin Resistance in Obesity”, Et Al 2021
“Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity”, 2021-11-22 (similar)
“Sexual Dimorphic Responses of C57BL/6 Mice to Fisetin or Dasatinib and Quercetin Cocktail Oral Treatment”, Et Al 2021
“Sexual dimorphic responses of C57BL/6 mice to Fisetin or Dasatinib and Quercetin cocktail oral treatment”, 2021-11-08 (similar)
“A Collective Analysis of Lifespan-extending Compounds in Diverse Model Organisms, and of Species Whose Lifespan Can Be Extended the Most by the Application of Compounds”, 2021
“A collective analysis of lifespan-extending compounds in diverse model organisms, and of species whose lifespan can be extended the most by the application of compounds”, 2021-10-21 (; similar)
“The Metabolic Roots of Senescence: Mechanisms and Opportunities for Intervention”, 2021
“The metabolic roots of senescence: mechanisms and opportunities for intervention”, 2021-10-18 (similar)
“Strategies for Targeting Senescent Cells in Human Disease”, Et Al 2021
“Strategies for targeting senescent cells in human disease”, 2021-10-07 (similar)
“Modulation of Fracture Healing by the Transient Accumulation of Senescent Cells”, Et Al 2021
“Modulation of fracture healing by the transient accumulation of senescent cells”, 2021-10-07 (similar)
“Fisetin for COVID-19 in Skilled Nursing Facilities: Senolytic Trials in the COVID Era”, Et Al 2021
“Fisetin for COVID-19 in skilled nursing facilities: Senolytic trials in the COVID era”, 2021-08-10 (similar)
“Senolytics and the Compression of Late-life Mortality”, 2021
“Senolytics and the compression of late-life mortality”, 2021-04-26 (similar)
“Procyanidin C1 Is a Natural Agent With Senolytic Activity against Aging and Age-related Diseases”, Et Al 2021
“Procyanidin C1 is a natural agent with senolytic activity against aging and age-related diseases”, 2021-04-14 (similar)
“Oxylipin Biosynthesis Reinforces Cellular Senescence and Allows Detection of Senolysis”, Et Al 2021
“Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis”, 2021-04-02 (similar)
“Whole-body Senescent Cell Clearance Alleviates Age-related Brain Inflammation and Cognitive Impairment in Mice”, Et Al 2021
“Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice”, 2021-01-20 (similar)
“The Quest to Slow Ageing through Drug Discovery”, Et Al 2020
“The quest to slow ageing through drug discovery”, 2020-05-28 (backlinks; similar)
“Senolytic Drugs: from Discovery to Translation”, 2020
“Senolytic drugs: from discovery to translation”, 2020 (backlinks; similar)
“A Look Back at 2019: Progress Towards the Treatment of Aging As a Medical Condition”, 2019
“A Look Back at 2019: Progress Towards the Treatment of Aging as a Medical Condition”, 2019-12-31 (; similar)
“Senolytics Decrease Senescent Cells in Humans: Preliminary Report from a Clinical Trial of Dasatinib plus Quercetin in Individuals With Diabetic Kidney Disease”, Et Al 2019
“Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease”, 2019-09-18 (similar)
“Metformin and Aging: A Review”, 2019
“Metformin and Aging: A Review”, 2019-09-13 (; backlinks; similar)
“Senolytic Treatment Targets Aberrant P21-expression to Restore Liver Regeneration in Adult Mice”, Et Al 2019
“Senolytic treatment targets aberrant p21-expression to restore liver regeneration in adult mice”, 2019-09-05 (similar)
“Galactose-modified Duocarmycin Prodrugs As Senolytics”, Et Al 2019
“Galactose-modified duocarmycin prodrugs as senolytics”, 2019-08-24 (similar)
“Senolytics Improve Physical Function and Increase Lifespan in Old Age”, Et Al 2018
“Investigation of Quercetin and Hyperoside As Senolytics in Adult Human Endothelial Cells”, Et Al 2017
“Investigation of quercetin and hyperoside as senolytics in adult human endothelial cells”, 2017-12-13 (similar)
“Targeting Cellular Senescence Prevents Age-related Bone Loss in Mice”, Et Al 2017
“Targeting cellular senescence prevents age-related bone loss in mice”, 2017 (similar)
“The Clinical Potential of Senolytic Drugs”, Et Al 2017
“The Clinical Potential of Senolytic Drugs”, 2017 (similar)
“Naturally Occurring P16(Ink4a)-positive Cells Shorten Healthy Lifespan”, Et Al 2016
“Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan”, 2016 (backlinks; similar)
Wikipedia
Miscellaneous
-
https://www.fightaging.org/archives/2018/09/thoughts-on-attending-raadfest-2018-in-san-diego/ -
https://www.frontiersin.org/articles/10.3389/fnagi.2021.646924/full -
https://www.jhep-reports.eu/article/S2589-5559(21)00077-X/fulltext -
https://www.longevity.technology/senescence-field-has-completely-exploded/ -
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(18)30373-6/fulltext -
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(18)30629-7/fulltext
Link Bibliography
-
https://www.nature.com/articles/s41467-022-32552-1: “SenMayo: A New Gene Set Identifies Senescent Cells and Predicts Senescence-associated Pathways across Tissues”, : -
2021-hanley.pdf: “Results of a 5-Year <em>n< / em>-of-1 Growth Hormone Releasing Hormone Gene Therapy Experiment”, Brian P. Hanley, Keith Brewer, George Church: -
https://onlinelibrary.wiley.com/doi/10.1111/acel.13528: “Deletion of SA Β-Gal+ Cells Using Senolytics Improves Muscle Regeneration in Old Mice”, : -
2021-suda.pdf: “Senolytic Vaccination Improves Normal and Pathological Age-related Phenotypes and Increases Lifespan in Progeroid Mice”, :