Melatonin Benefits, Dosage, and Side Effects
FDA Adverse Events Reporting System (FAERS) Public Dashboard: ‘Vitamin D’
Zgg040 491..497
Melatonin Treatment for Age-Related Insomnia
Melatonin in sleep disorders and jet-lag
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958662/
Melatonin for Treatment of Sleep Disorders
https://www.mayoclinic.org/health/melatonin/NS_patient-melatonin/DSECTION=evidence
2005-brzezinski.pdf
Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysis
Exogenous Melatonin for Sleep Problems in Individuals With Intellectual Disability: a Meta-Analysis
2013-keegan.pdf
Meta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders
https://www.journalsleep.org/Resources/Documents/2012abstractsupplement.pdf
Melatonin Can Help Seniors Get More Sleep
Melatonin in aging and disease -multiple consequences of reduced secretion, options and limits of treatment
Efficacy and safety of prolonged-release melatonin for insomnia in middle-aged and elderly patients with hypertension: a combined analysis of controlled clinical trials
Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysis
The efficacy and safety of exogenous melatonin for primary sleep disorders. A meta-analysis
Melatonin for Treatment of Sleep Disorders: Summary
Prolonged release melatonin in the treatment of primary insomnia: evaluation of the age cut-off for short-term and long-term response
Pharmacological and Non-Pharmacological Management of Sleep Disturbance in Children: An Australian Paediatric Research Network Survey
https://web.archive.org/web/20110805001118/http://www.mayoclinic.com/health/melatonin/NS_patient-melatonin/DSECTION=safety
https://www.fda.gov/ICECI/EnforcementActions/WarningLetters/ucm201435.htm
https://naturalmedicines.therapeuticresearch.com/index-abstract.asp?create-abstract=patient-melatonin.asp&title=Melatonin
The History of Sleep Before the Industrial Revolution
https://www.amazon.com/At-Days-Close-Night-Times/dp/0393329011/
What Is a ‘Natural’ Sleep Pattern?
Why We Nap: Evolution, Chronobiology, and Functions of Polyphasic and Ultrashort SLeep
Impact of Sleep Debt on Metabolic and Endocrine Function
Brain Responds Same to Acute and Chronic Sleep Loss, Research Finds
Daylight Savings Time and Traffic Accidents
1996-coren.pdf
2003-vandongen.pdf
Sleep Is More Important Than Food
2005-dement.html.maff
Experimental ‘Jet Lag’ Inhibits Adult Neurogenesis and Produces Long-Term Cognitive Deficits in Female Hamsters
https://web.archive.org/web/20120620034226/http://blog.myzeo.com/sleep-by-night-of-the-week/
How Little Sleep Can You Get Away With?
A Sleep Diary and Questionnaire Study of Naturally Short Sleepers
The Impact of Sleep Deprivation on Decision Making: A Review
Neurocognitive Consequences of Sleep Deprivation
We are Chronically Sleep Deprived
https://link.springer.com/content/pdf/10.3758/BF03333140.pdf
2012-matricciani.pdf
https://www.wsj.com/articles/SB10001424052702304657804576401890078537246
Entrainment of the Human Circadian Clock to the Natural Light-Dark Cycle
https://www.psychiatrictimes.com/print/article/10168/54471?pageNumber=1&printable=true
1995-palinkas.pdf
Lost in Time in the Antarctic Ice Age
Peak Performance: Why Records Fall
The role of deliberate practice in the acquisition of expert performance
Can Small Shifts in Circadian Phase Affect Performance?
Verses, Composed during a Night of Insomnia...
The Algernon Argument
Melatonin: A ‘Magic’ Sleeping Pill for Children? Pediatricians Worry As Parents Increasingly Use Melatonin to Deal With Nighttime Restlessness
Relationships between Hours of Sleep and Health-Risk Behaviors in US Adolescent Students
Intrinsic period and light intensity determine the phase relationship between melatonin and sleep in humans
‘Out of the Lab and into the Bathroom: Evening Short-Term Exposure to Conventional Light Suppresses Melatonin and Increases Alertness Perception’, 2013
Exposure to Bright Light during Evening Class Hours Increases Alertness among Working College Students
https://www.webmd.com/sleep-disorders/news/20110119/light-exposure-may-cut-production-of-melatonin
Melatonin Production Falls If the Lights Are On
2007-navara.pdf
All That Tech Is Hurting Your Sleep, Researchers Say: The National Sleep Foundation Finds That Using Technology Before Bed Can Disrupt Sleep. Fingers Are Pointed at Laptops, Mobile Phones, and Video Games
Evening Use of Light-Emitting Ereaders Negatively Affects Sleep, Circadian Timing, and Next-Morning Alertness
Light Level and Duration of Exposure Determine the Impact of Self-Luminous Tablets on Melatonin Suppression
Effects of LED-Backlit Computer Screen and Emotional Self-Regulation on Human Melatonin Production
Dual n-Back FAQ
2011-munch.pdf
GoodTherapy
Preliminary Evidence That Light through the Eyelids Can Suppress Melatonin and Phase Shift Dim Light Melatonin Onset
What’s in a Color? The Unique Human Health Effects of Blue Light
In Eyes, a Clock Calibrated by Wavelengths of Light
Light and Health Research Programs
Nocturnal Light Exposure Impairs Affective Responses in a Wavelength-Dependent Manner
Limiting the Impact of Light Pollution on Human Health, Environment and Stellar Visibility
F.lux: Sleep Research
Blue-Blocking Glasses To Improve Sleep And ADHD Symptoms Developed
Blue Blocker Glasses As a Countermeasure for Alerting Effects of Evening Light-Emitting Diode Screen Exposure in Male Teenagers
AMBER LENSES TO BLOCK BLUE LIGHT AND IMPROVE SLEEP: A RANDOMIZED TRIAL
https://psycheducation.org/depression/LightDark.htm
Zeo sleep self-experiments
Quantified Self Boston Meetup #5, The Science of Sleep: Recap
The Measured Life: Do You Know How Much REM Sleep You Got Last Night? New Types of Devices That Monitor Activity, Sleep, Diet, and Even Mood Could Make Us Healthier and More Productive
http://jonls.dk/redshift/
F.lux: Software to Make Your Life Better
https://web.archive.org/web/20130120050705/http://blog.wakemate.com/2011/03/21/using-electronics-before-bed-is-detrimental-but-f-lux-might-have-the-solution/
https://news.ycombinator.com/item?id=2369788
Sleep Experiment - A Month With No Artificial Light
https://www.overcomingbias.com/p/the-future-is-brighthtml
2013-czeisler.pdf
https://www.sciencenews.org/view/generic/id/40170/title/Darkness%2C_melatonin_may_stall_breast_and_prostate_cancers
The Dark Side
Lower Melatonin Levels May Affect Infant Mental Capacity, Study
https://edition.cnn.com/2011/TRAVEL/03/24/dc.air.traffic.suspension/index.html
zeo#melatonin-analysis
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education-is-not-about-learning#school-hours
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MELATONIN
MELATONIN
Neuroimmunotherapy With Low-Dose Subcutaneous Interleukin-2 plus Melatonin in AIDS Patients With CD4 Cell Number below 200 Cells/mm3: a Biological Phase-II Study
https://www.tandfonline.com/doi/abs/10.1081/CBI-120004546
https://www.nejm.org/doi/full/10.1056/NEJM200010123431503#t=article
Effects of Low Oral Doses of Melatonin Given 2-4 Hours Before Habitual Bedtime, on Sleep in Normal Young Humans
2011-gooneratne.pdf
The Effect of Melatonin Administration on Pituitary Hormone Secretion in Man
HealthNewsDigest.com
Melatonin Supplements Review & Top Picks
https://www.amazon.com/gp/product/B000638OT0/
https://www.amazon.com/gp/product/B0014UE98E/
https://www.amazon.com/gp/product/B001G7QWJY/
The Instrumental Value of Your Own Time
zeo#value-of-information-voi
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context]
https://www.lesswrong.com/posts/XYA9nBud8joDjTy86/case-study-melatonin?commentId=9vgs5bGxY8H24AjCN
Akrasia, Hyperbolic Discounting, and Picoeconomics
Applied Picoeconomics
Anti-Akrasia Remote Monitoring Experiment
Working Best at Coffee Shops
https://news.ycombinator.com/item?id=2462683
https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.95.3101&rep=rep1&type=pdf
Improving The Akrasia Hypothesis
Benefits of Melatonin?
Dietary Supplement Use in the United States, 2003–2006
Dietary Supplement Use among U.S. Adults Has Increased Since NHANES III (1988–1994)
Vitamin Pills: A False Hope?
Lung Cancer: Association With Supplemental Multivitamin, Vitamin C & E, and Folate Intake
Effects of Long-Term Vitamin E Supplementation on Cardiovascular Events and Cancer
Multivitamin Use and Risk of Cancer and Cardiovascular Disease in the Women’s Health Initiative Cohorts
Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer: The Women’s Health Study: A Randomized Controlled Trial
https://www.nejm.org/doi/full/10.1056/NEJM199404143301501
2005-stevens.pdf
Vitamin and mineral use and risk of prostate cancer: the case-control surveillance study
Multivitamin Use and Breast Cancer Incidence in a Prospective Cohort of Swedish Women
Multivitamin Supplement Use and Risk of Breast Cancer: A Meta-Analysis
Multivitamin Use and Colon Cancer Mortality in the Cancer Prevention Study II Cohort (United States)
Multivitamin Use, Folate, and Colon Cancer in Women in the Nurses’ Health Study
Multivitamin Use and Mortality in a Large Prospective Study
2012-li.pdf
Use of Supplements of Multivitamins, Vitamin C, and Vitamin E in Relation to Mortality
Multivitamin Use and the Risk of Mortality and Cancer Incidence: the Multiethnic Cohort Study
Antioxidant Supplements for Prevention of Mortality in Healthy Participants and Patients With Various Diseases
Dietary Supplements and Mortality Rate in Older Women: The Iowa Women’s Health Study
Role of Multivitamins and Mineral Supplements in Preventing Infections in Elderly People: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Multivitamins in the Prevention of Cancer in Men: The Physicians' Health Study II Randomized Controlled
Vitamins E and C in the Prevention of Prostate and Total Cancer in Men: The Physicians' Health Study II Randomized Controlled Trial
Lack of Effect of Long-Term Supplementation With Beta Carotene on the Incidence of Malignant Neoplasms and Cardiovascular Disease
Vitamins C and E and Beta Carotene Supplementation and Cancer Risk: A Randomized Controlled Trial
Antioxidant Supplements to Prevent Mortality
Meta-Regression Analyses, Meta-Analyses, and Trial Sequential Analyses of the Effects of Supplementation with Beta-Carotene, Vitamin A, and Vitamin E Singly or in Different Combinations on All-Cause Mortality: Do We Have Evidence for Lack of Harm?
https://www.overcomingbias.com/p/supplements-killhtml
Diet - Lifestyle - Disease - Health - Medicine - H.R.T. - Hormone-Replacement Therapy
Concern About Antioxidants and Breast Cancer
Vitamin C antagonizes the cytotoxic effects of antineoplastic drugs
Phys Ed: Free the Free Radicals
Vitamins Found to Curb Exercise Benefits
https://exrx.net/Nutrition/Antioxidants/Antioxidants
Vitamin C and E supplementation hampers cellular adaptation to endurance training in humans: a double-blind, randomized, controlled trial
Antioxidants and Exercise: More Harm Than Good?
Antioxidants and Skeletal Muscle Performance: "Common Knowledge" versus Experimental Evidence
Taking Vitamin Pills May Undermine Motivation to Reduce Smoking
A randomized experiment to examine unintended consequences of dietary supplement use among daily smokers: taking supplements reduces self-regulation of smoking
Even If You Have a Nail, Not All Hammers Are the Same
Modafinil
Case Study: Melatonin
https://www.lesswrong.com/
https://www.reddit.com/r/LessWrong/comments/blf7w/experiences_with_taking_melatonin/
https://www.lesswrong.com/posts/hMv7JhPMN8SuSrk7m/open-thread-april-2010?commentId=S2df4tHk3c77yAftx
Generalizing From One Example
https://news.ycombinator.com/item?id=5245358
http://de1.erowid.org/experiences/subs/exp_Melatonin.html
https://isomerdesign.com/pihkal/read/tk/35
https://www.reddit.com/r/Supplements/comments/mr0h1/taking_melatonin_forever/
https://news.ycombinator.com/item?id=6495358
CNS Drugs 2007; 21 (12): 995–1018
Melatonin: Much More Than You Wanted To Know
Evening home lighting adversely impacts the circadian system and sleep
https://www.reddit.com/r/slatestarcodex/comments/p8r1y1/does_melatonin_help_me_sleep_longer_a_blinded/
Abnormal 24 Hour Pattern of Melatonin Secretion in Depression
A Chronobiological Study of Melatonin and Cortisol Secretion in Depressed Subjects: Plasma Melatonin, a Biochemical Marker in Major Depression
Circadian Rhythm of Plasma Melatonin in Endogenous Depression
Differences in nocturnal melatonin secretion between melancholic depressed patients and control subjects
Patterns of Melatonin Rhythms in Depression
Changes in Melatonin Levels but Not Cortisol Levels Are Associated With Depression in Patients With Eating Disorders
Nocturnal Serum Melatonin Profile in Major Depression in Children and Adolescents
Circadian Profiles of Melatonin in Melancholic Depressed Patients and Healthy Subjects in Relation to Cortisol Secretion and Sleep
Serum Melatonin and Urinary 6-Sulfatoxymelatonin in Major Depression
Phase relationships between core body temperature, melatonin, and sleep are associated with depression severity: further evidence for circadian misalignment in non-seasonal depression
2011-dallaspezia.pdf
Chronic Dim Light at Night Provokes Reversible Depression-Like Phenotype: Possible Role for TNF
1997-fainstein.pdf
Melatonin effects on sleep, mood, and cognition in elderly with mild cognitive impairment
Melatonin Treatment of Winter Depression: a Pilot Study
Use of slow-release melatonin in treatment-resistant depression
2001-bellipanni.pdf
Melatonin in Psychiatric Disorders: A Review on the Melatonin Involvement in Psychiatry
2005-danilenko.pdf
The Circadian Basis of Winter Depression
2009-garzon.pdf
Bright-Light Therapy in the Treatment of Mood Disorders
Reduced phase-advance of plasma melatonin after bright morning light in the luteal, but not follicular, menstrual cycle phase in premenstrual dysphoric disorder: an extended study
2005-bellipanni.pdf
A Randomized Double-Blind Placebo-Controlled Trial of Treatment As Usual plus Exogenous Slow-Release Melatonin (6 Mg) or Placebo for Sleep Disturbance and Depressed Mood
An Exploratory Study of Combination Buspirone and Melatonin SR in Major Depressive Disorder (MDD): A Possible Role for Neurogenesis in Drug Discovery
2013-delfabbro.pdf#page=33
The Therapeutic or Prophylactic Effect of Exogenous Melatonin against Depression and Depressive Symptoms: A Systematic Review and Meta-Analysis
Novel Melatonin-Based Therapies: Potential Advances in the Treatment of Major Depression
Circadian Rhythms, Melatonin and Depression
A Benefit-Risk Assessment of Agomelatine in the Treatment of Major Depression
Negative Effects of Melatonin on Depression
Melatonin for the Treatment of Sleep Disturbances in Major Depressive Disorder