Bibliography (146):

  1. Junkfood Science: Calorie Restrictive Eating for Longer Life? The Story We Didn’t Hear in the News

  2. Caloric Restriction Reduces Age-Related and All-Cause Mortality in Rhesus Monkeys

  3. Why Correlation Usually ≠ Causation

  4. The Replication Crisis: Flaws in Mainstream Science § Animal Models

    [Transclude the forward-link's context]

  5. Metformin Inhibits Mitochondrial Adaptations to Aerobic Exercise Training in Older Adults

  6. February 2021 News § Semaglutide

    [Transclude the forward-link's context]

  7. CURATED DATABASE OF GEROPROTECTORS

  8. Use of Glucosamine and Chondroitin in Relation to Mortality

  9. Dietary Magnesium Intake Is Inversely Associated With Mortality in Adults at High Cardiovascular Disease Risk

  10. Low-Dose Lithium Uptake Promotes Longevity in Humans and Metazoans

  11. https://www.nejm.org/doi/full/10.1056/NEJMoa1511939

  12. https://www.nejm.org/doi/suppl/10.1056/NEJMoa1511939/suppl_file/nejmoa1511939_appendix.pdf#page=2

  13. Primary Prevention of Cardiovascular Disease With a Mediterranean Diet Supplemented With Extra-Virgin Olive Oil or Nuts

  14. 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity

  15. Effects of Castration on the Life Expectancy of Contemporary Men

  16. Effects of Castration on the Life Expectancy of Contemporary Men

  17. Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice

  18. Dogs Test Drug Aimed at Humans’ Biggest Killer: Age

  19. https://link.springer.com/article/10.1007/s11357-017-9972-z

  20. Are the Benefits of Moderate Drinking a Myth?

  21. Mortality Hazard Rates and Life Expectancy

  22. Computational Analysis of Lifespan Experiment Reproducibility

  23. A Weakly Informative Default Prior Distribution for Logistic and Other Regression Models

  24. Performance of informative priors skeptical of large treatment effects in clinical trials: A simulation study

  25. Vitamin D and Calcium: A Systematic Review of Health Outcomes (Update)

  26. Vitamin D and Multiple Health Outcomes: Umbrella Review of Systematic Reviews and Meta-Analyses of Observational Studies and Randomized Trials

  27. Genetic variants and associations of 25-hydroxyvitamin D concentrations with major clinical outcomes

  28. https://academic.oup.com/clinchem/article/59/5/793/5622179

  29. https://academic.oup.com/clinchem

  30. Genetically Low Vitamin D Concentrations and Increased Mortality: Mendelian Randomization Analysis in Three Large Cohorts

  31. https://scholar.google.com/scholar?q=%22vitamin+d%22+all-cause+mortality+meta-analysis&btnG=&as_sdt=0%2C21&as_ylo=2012

  32. Vitamin D Supplementation and Total Mortality: A Meta-Analysis of Randomized Controlled Trials

  33. Extraskeletal Effects of Vitamin D in Older Adults: Cardiovascular Disease, Mortality, Mood, and Cognition

  34. Vitamin D and Cardiovascular Outcomes: A Systematic Review and Meta-Analysis

  35. Calcium supplements with or without vitamin D and risk of cardiovascular events: reanalysis of the Women’s Health Initiative limited access dataset and meta-analysis

  36. Vitamin D with calcium reduces mortality: patient level pooled analysis of 70,528 patients from eight major vitamin D trials

  37. Meta-analysis of long-term vitamin D supplementation on overall mortality

  38. 2013-lazzeroni.pdf

  39. Vitamin D Supplementation for Prevention of Cancer in Adults (Review)

  40. Vitamin D Supplementation for Prevention of Mortality in Adults

  41. 2014-bolland.pdf

  42. Vitamin D and Risk of Cause Specific Death: Systematic Review and Meta-Analysis of Observational Cohort and Randomized Intervention Studies

  43. Vitamin D Status and Ill Health: a Systematic Review

  44. 2014-autier-appendix.pdf

  45. Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men

  46. A meta-analysis of high dose, intermittent vitamin D supplementation among older adults

  47. 1983-inkovaara.pdf

  48. 1985-corless.pdf

  49. 1996-lips.pdf

  50. https://www.columbia.edu/itc/hs/pubhealth/p8403/readings/lips.pdf

  51. 1998-komulainen.pdf

  52. Prevention of Femoral and Lumbar Bone Loss with Hormone Replacement Therapy and Vitamin D3 in Early Postmenopausal Women: A Population-Based 5–Year Randomized Trial

  53. https://onlinelibrary.wiley.com/doi/10.1359/jbmr.2002.17.4.709/full

  54. https://onlinelibrary.wiley.com/doi/10.1359/jbmr.2003.18.2.343/full

  55. https://www.sciencedirect.com/science/article/pii/S0002916523057817

  56. A Randomized, Controlled Trial of Quadriceps Resistance Exercise and Vitamin D in Frail Older People: The Frailty Interventions Trial in Elderly Subjects (FITNESS)

  57. Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomized double blind controlled trial

  58. 2004-avenell.pdf

  59. https://ageing.oxfordjournals.org/content/33/1/45.full.pdf+html

  60. A Randomized Controlled Trial of Vitamin D3 Supplementation in African American Women

  61. Should Older People in Residential Care Receive Vitamin D to Prevent Falls? Results of a Randomized Trial

  62. Oral vitamin D3 and calcium for secondary prevention of low-trauma fractures in elderly people (Randomized Evaluation of Calcium Or vitamin D, RECORD): a randomized placebo-controlled trial

  63. 2007-broe.pdf

  64. https://academic.oup.com/ageing/article/36/5/507/40586

  65. Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial

  66. 2007-lyons.pdf

  67. https://academic.oup.com/rheumatology/article/46/12/1852/1789226

  68. https://academic.oup.com/ageing/article/37/1/25/24810

  69. https://link.springer.com/article/10.1007/s00198-007-0465-2

  70. Effects of Ergocalciferol Added to Calcium on the Risk of Falls in Elderly High-Risk Women

  71. Effects of Calcium and Vitamin D Supplementation on Hip Bone Mineral Density and Calcium-Related Analytes in Elderly Ambulatory Australian Women: A Five-Year Randomized Controlled Trial

  72. Once-Weekly Dose of 8400 IU Vitamin D3 Compared With Placebo: Effects on Neuromuscular Function and Tolerability in Older Adults With Vitamin D Insufficiency

  73. Annual High-Dose Oral Vitamin D and Falls and Fractures in Older Women: A Randomized Controlled Trial

  74. https://onlinelibrary.wiley.com/doi/10.1002/jbmr.524/full

  75. Vitamin D3 and Calcium to Prevent Hip Fractures in Elderly Women

  76. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2539939/pdf/bmj00437-0035.pdf

  77. https://www.columbia.edu/itc/hs/pubhealth/p8403/readings/dawson-hughes.pdf

  78. 1998-baeksgaard.pdf

  79. 1999-krieg.pdf

  80. 2002-chapuy.pdf

  81. https://onlinelibrary.wiley.com/doi/10.1359/JBMR.040511/full

  82. 2005-brazier.pdf

  83. Randomized controlled trial of calcium and supplementation with cholecalciferol (vitamin D3) for prevention of fractures in primary care

  84. 2006-jackson.pdf

  85. https://www.nejm.org/doi/full/10.1056/NEJMoa055222

  86. https://circ.ahajournals.org/content/115/7/846.full

  87. https://onlinelibrary.wiley.com/doi/10.1359/jbmr.070116/full

  88. https://onlinelibrary.wiley.com/doi/10.1002/jbmr.48/full

  89. CRAN: Package Bayesmeta

  90. https://www.amazon.com/gp/product/B0050MYHBQ/

  91. https://www.cochranelibrary.com/doi/10.1002/14651858.CD007469.pub2/pdf

  92. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410276/figure/F3/

  93. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410276/table/T1/

  94. ‘I Think There’s No Doubt That Insulin Is Pro-Cancer”, Watson Says, with respect to the Link between Obesity, Diabetes and Cancer. “It’s As Good a Hypothesis As We Have Now.’ Watson Takes Metformin for Cancer Prevention; among Its Many Effects, Metformin Works to Lower Insulin Levels.

  95. The Man Who Wants to Beat Back Aging: Nir Barzilai Hopes to Persuade FDA to Bless the Proposed Anti-Aging Trial, Which Is Unconventional in Its Goals and Design.

  96. Dr. Nir Barzilai on the TAME Study

  97. Anti-Ageing Pill Pushed As Bona Fide Drug: Regulators Asked to Consider Ageing a Treatable Condition

  98. Metformin in Longevity Study (MILES)

  99. Metformin As a Tool to Target Aging

  100. https://www.cochranelibrary.com/doi/10.1002/14651858.CD002966.pub3/epdf/standard

  101. Cardiovascular Outcomes in Trials of Oral Diabetes Medications: A Systematic Review Acute Coronary Syndromes

  102. 2011-lamanna.pdf

  103. 2012-stevens.pdf

  104. Metformin reduces all-cause mortality and diseases of ageing independent of its effect on diabetes control: A systematic review and meta-analysis

  105. Metformin As a Geroprotector

  106. Metformin in obesity, cancer and aging: addressing controversies

  107. Metformin: do we finally have an anti-aging drug?

  108. Metformin and Aging: A Review

  109. 2014-bannister.pdf

  110. Metformin Dosage Guide + Max Dose, Adjustments

  111. Metformin (Oral Route) Proper Use

  112. https://www.goodrx.com/metformin

  113. Not Found

  114. Metformin Side Effects: Common, Severe, Long Term

  115. 2002-fda-metforminhydrochloridetablets-prescribinginformation.pdf

  116. Metformin and Fatal Lactic Acidosis

  117. The Value of Health and Longevity

  118. A Multi-Tissue Full Lifespan Epigenetic Clock for Mice

  119. Epigenetic clocks: A review

  120. TRIIM: Reversal of epigenetic aging and immunosenescent trends in humans

  121. Reversal of Epigenetic Age with Diet and Lifestyle in a Pilot Randomized Clinical Trial

  122. The economic value of targeting aging

  123. https://www.longevityhistory.com/book/indexb.html

  124. Which Risks of Dying Are Worth Taking?

  125. Who By Very Slow Decay

  126. GBD Compare

  127. What Does a 13% Increased Risk of Death Mean?

  128. The quest to slow ageing through drug discovery