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Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomized, phase 3 trial
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https://clinicaltrials.gov/study/NCT03954834
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Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes [SURPASS-2]
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https://clinicaltrials.gov/study/NCT03987919
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Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomized, open-label, parallel-group, phase 3 trial
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https://clinicaltrials.gov/study/NCT03882970
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Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomized, open-label, parallel-group, multicenter, phase 3 trial
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https://clinicaltrials.gov/study/NCT03730662
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Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial
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https://clinicaltrials.gov/study/NCT04039503
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Lilly’s tirzepatide delivered up to 22.5% weight loss in adults with obesity or overweight in SURMOUNT-1
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Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicenter, randomized, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial
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FDA approves first oral GLP-1 treatment for type 2 diabetes
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Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 2.4mg for weight management: a randomized, controlled, phase 1b trial
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