“Features of a Successful Therapeutic Fast of 382 Days’ Duration”, 1973-03-01 (; similar):
A 27-year-old male patient fasted under supervision for 382 days and has subsequently maintained his normal weight. Blood glucose concentrations around 30 mg/100 ml were recorded consistently during the last 8 months, although the patient was ambulant and attending as an out-patient. Responses to glucose and tolbutamide tolerance tests remained normal. The hyperglycaemic response to glucagon was reduced and latterly absent, but promptly returned to normal during carbohydrate refeeding. After an initial decrease was corrected, plasma potassium levels remained normal without supplementation. A temporary period of hypercalcaemia occurred towards the end of the fast. Decreased plasma magnesium concentrations were a consistent feature from the first month onwards. After 100 days of fasting there was a marked and persistent increase in the excretion of urinary cations and inorganic phosphate, which until then had been minimal. These increases may be due to dissolution of excessive soft tissue and skeletal mass. Prolonged fasting in this patient had no ill-effects.
…During the 382 days of the fast, the patient’s weight decreased 456 → 180lb. 5 years after undertaking the fast, Mr A.B.’s weight remains around 196lb…The amount of weight lost and the rate of loss were not strikingly different from that of an earlier patient (Stewart, 1966) who reduced his weight 432 → 235lb during 350 days of intermittent starvation.
…We wish to express our gratitude to Mr A. B. for his cheerful cooperation and steadfast application to the task of achieving a normal physique.