“Psychiatric Genomics: An Update and an Agenda”, Patrick F. Sullivan, Arpana Agrawal, Cynthia M. Bulik, Ole A. Andreassen, Anders Børglum, Gerome Breen, Sven Cichon, Howard J. Edenberg, Stephen V. Faraone, Joel Gelernter, Carol A. Mathews, Caroline M. Nievergelt, Jordan Smoller, Michael C. O’Donovan, for the Psychiatric Genomics Consortium2017-03-10 (, ; similar)⁠:

The Psychiatric Genomics Consortium (PGC) is the largest consortium in the history of psychiatry. In the past decade, this global effort has delivered a rapidly increasing flow of new knowledge about the fundamental basis of common psychiatric disorders, particularly given its dedication to rapid progress and open science. The PGC has recently commenced a program of research designed to deliver “actionable” findings—genomic results that (a) reveal the fundamental biology, (b) inform clinical practice, and (c) deliver new therapeutic targets. This is the central idea of the PGC: to convert the family history risk factor into biologically, clinically, and therapeutically meaningful insights. The emerging findings suggest that we are entering into a phase of accelerated translation of genetic discoveries to impact psychiatric practice within a precision medicine framework.

Collaborators

PGC Coordinating Committee: Mark Daly, Michael Gill, John Kelsoe, Karestan Koenen, Douglas Levinson, Cathryn Lewis, Ben Neale, Danielle Posthuma, Jonathan Sebat, and Pamela Sklar.