“Meta-Research: A Comprehensive Review of Randomized Clinical Trials in Three Medical Journals Reveals 396 Medical Reversals”, 2019-06-11 (; backlinks; similar):
The ability to identify medical reversals and other low-value medical practices is an essential prerequisite for efforts to reduce spending on such practices.
Through an analysis of more than 3000 randomized controlled trials (RCTs) published in 3 leading medical journals (the Journal of the American Medical Association, the Lancet, and the New England Journal of Medicine), we have identified 396 medical reversals.
Most of the studies (92%) were conducted on populations in high-income countries, cardiovascular disease was the most common medical category (20%), and medication was the most common type of intervention (33%).