“Age Normalized Testosterone Peaks at Series B for Male Startup Founders”, Jordan Moradian, Michael Dubrovsky, Megha Sama, Pavel Korecky, Sidarth Kulkarni, Yaniv Goder, Diedrik Vermeulen2024-11-05 (; similar)⁠:

In a study of 107 male Y Combinator founders, a surprising correlation between age-normalized testosterone and company stage was uncovered. Testosterone, a hormone associated with confidence, dominance, and drive, increased by 55.7% from pre-seed to seed funding, peaking at the Series B stage, where levels were 99.6% higher than pre-seed.

After Series B funding, testosterone was observed to drop by 42.2%, coinciding with a spike in cortisol levels.

This age-normalized biomarker analysis supports the dual-hormone hypothesis, illustrating that early startup success fosters feelings of dominance and confidence, while later-stage pressures and stresses erode these feelings.

An alternative interpretation of the data, which suggests the opportunity for a longitudinal study, is that male founders with higher testosterone are more likely to raise larger rounds of funding.