“History of Iterated Embryo Selection”, Gwern2019-01-18 (R, economics, genetic correlation, evolution, decision theory, order statistics, power analysis, forecasting, transhumanism)⁠:

The multiple-invention (>3) history of the idea of extremely-powerful embryo selection by using gametogenesis to run many ‘generations’ in vitro.

The idea of iterated embryo selection—conducing multiple generations of embryo selection in a petri dish by exploiting gametogenesis or stem cells—has a complicated history. Tracing relevant papers back to 1989_35ya, the idea appears to have been invented independently at least 4

A predecessor was introduced by Georges & Massey1991 as “velogenetics”. Velogenetics led to what appears to be the first invention of IES, Haley & Visscher1998’s “whizzogenetics”. It was then invented in 2009_15ya by Carl Shulman as “iterated embryo selection”/“IES”. It was reinvented a third time by Sparrow2013 as “in vitro eugenics”. And it was reinvented up to 3× in 2018, as “in vitro breeding”, by Bogliotti et al 2018/Goszczynski et al 2018/Hou et al 2018 (whose relationship is unclear, as the latter two claim novelty but publish not just the same idea but same name, while the former, published before them and giving said name & idea, nevertheless does not claim novelty).

• Betteridge Et Al 1989
• Georges & Massey1991
• Haley & Visscher1998
• Shulman2009
• Sparrow2013
• Bogliotti Et Al 2018
• Goszczynski Et Al 2018
• Hou Et Al 2018