“Polygenic Risk Scores for Schizophrenia and Bipolar Disorder Predict Creativity”, Robert A. Power, Stacy Steinberg, Gyda Bjornsdottir, Cornelius A. Rietveld, Abdel Abdellaoui, Michel M. Nivard, Magnus Johannesson, Tessel E. Galesloot, Jouke J. Hottenga, Gonneke Willemsen, David Cesarini, Daniel J. Benjamin, Patrik K. E. Magnusson, Fredrik Ullén, Henning Tiemeier, Albert Hofman, Frank J. A. van Rooij, G. Bragi Walters, Engilbert Sigurdsson, Thorgeir E. Thorgeirsson, Andres Ingason, Agnar Helgason, Augustine Kong, Lambertus A. Kiemeney, Philipp Koellinger, Dorret I. Boomsma, Daniel F. Gudbjartsson, Hreinn Stefansson, Kari Stefansson2015-06-08 (, , , ; backlinks; similar)⁠:

We tested whether polygenic risk scores for schizophrenia and bipolar disorder would predict creativity.

Higher scores were associated with artistic society membership or creative profession in both Icelandic (p = 5.2 × 10−6 and 3.8 × 10−6 for schizophrenia and bipolar disorder scores, respectively) and replication cohorts (p = 0.0021 and 0.00086).

This could not be accounted for by increased relatedness between creative individuals and those with psychoses, indicating that creativity and psychosis share genetic roots.

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Polygenic Risk Scores for Schizophrenia and Bipolar Disorder Predict Creativity