“A ’Trip’ to the Intensive Care Unit: An Intravenous Injection of Psilocybin”, 2021-05-01 (; similar):
Here, we describe a case of a 30-year-old man who injected psilocybin intravenously resulting in an extended stay in the intensive care unit because of multiple-system organ failure.
…History gathered from his family was remarkable for recent non-adherence with his prescribed psychotropics (risperidone and valproate) and subsequent cycling between depressive and manic states. He had reportedly been researching ways to self-treat his opioid dependence and depression.
In his reading, he encountered reports of therapeutic effects of microdosing lysergic acid diethylamide and hallucinogenic psilocybin mushrooms prompting him to inject what he had named “mushroom tea”–psilocybin mushrooms boiled down in water. He then “filtered” this substance by drawing it through a cotton swab before directly injecting the solution intravenously. Over the next several days, he developed lethargy, jaundice, diarrhea, nausea, and hematemesis before he was found by his family and taken to the emergency department.
…He was then transferred to the intensive care unit for evidence of multi-organ failure…His hospital course was further complicated by septic shock and acute respiratory failure requiring intubation on hospital day 2…Cultures confirmed both bacterial (ultimately cultured as Brevibacillus) and fungal infections (ultimately cultured and DNA identified by a specialist laboratory as Psilocybe cubensis—ie. the species of mushroom he had injected was now growing from his blood).