“Modafinil Use in Patients With a Primary Psychiatric Illness”, Warwick Black, Peter Hoey, Thomas Mayze2010-05-20 (, , )⁠:

We report 4 individuals with a variety of psychiatric diagnoses whose symptoms of fatigue, sleepiness or hypoarousal were treated successfully with modafinil. In each case the patient remains on modafinil therapy, with no important adverse events reported to date.

…The first patient had a 30 year history of bipolar disorder type 1…The second patient had experienced massive cerebral trauma requiring a long period of rehabilitation…The third patient is a 70 year old male with treatment-resistant depression characterized by severe fatigue and a possible obsessive-compulsive spectrum disorder…Finally, a 32 year old female patient presented with severe uncontrolled trichotillomania, and depressive symptoms.