“The Effects of Fluoride in Drinking Water”, Linuz Aggeborn, Mattias Öhman2021-01-13 (; similar)⁠:

Water fluoridation is a common but debated public policy.

In this paper, we use Swedish registry data to study the causal effects of fluoride in drinking water. We exploit exogenous variation in natural fluoride stemming from variation in geological characteristics at water sources to identify its effects.

First, we reconfirm the long-established positive effect of fluoride on dental health. Second, we estimate a zero effect on cognitive ability in contrast to several recent debated epidemiological studies. Third, fluoride is furthermore found to increase labor income. This effect is foremost driven by individuals from a lower socioeconomic background.

…Let us continue to our main results. We begin with cognitive ability for men born 19852198737ya. Our conclusion from Table 4 is that fluoride does not affect cognitive ability. Column 1 displays the unconditional treatment effect. In columns 2 and 3, we add fixed effects for cohort and municipality of birth. We then include parental covariates, which results in a reduced sample since we have data on fathers’ cognitive ability only from 1969 and onward. To make the samples comparable with and without these covariates, we run column 4 for the same sample as in column 5. We also run two subsample analyses: in column 6, we run the analysis for those who have lived in the same SAMS in a municipality for the entire period from age 0 to 18, and in column 7 we restrict the sample to those who have moved only within a municipality.

Table 4: cognitive ability

Looking at the estimates, they are very small and often not statistically-significantly different from zero. Sometimes the estimates are negative and sometimes positive, but they are always close to zero. If we take the largest negative point estimates (−0.0047, col. 1) and the largest standard error for that specification (0.0045), the 95% confidence interval would be −0.014 to 0.004. We may thus rule out negative effects larger than 0.14 standard deviations in cognitive ability if fluoride is increased by 1 milligram/liter (the level often considered when artificially fluoridating the water).

…We now continue with the long-term outcome of annual labor income in 2014 for individuals born 19857199232ya. Given our results for cognitive ability, we do not expect negative effects of fluoride. However, positive effects are possible given the results found for dental health.

The results are presented in Table 5. The point estimates are often statistically-significant, and the coefficients are always positive. Taking column 6 as an example, where all covariates and fixed effects are included, we find that the point estimate equals 0.0044, meaning that income increases by 4.4% if fluoride is increased by 1 milligram/liter. These reduced form estimates may be compared with Glied & Neidell2010, who, by using American data, found that women who drink fluoridated water have on average 4% higher earnings. Our estimated effect on income may also be compared with estimated education premiums. The return of one additional year of education yields an increase in income by 6%–10%, according to the instrumental variable estimates in the review in Card (199925ya). An increase in fluoride by 1 milligram/liter would thus yield a similar increase as roughly half a year of additional education. Nonlinear specifications are presented in Figure A1 and tables A8–A10, which overall supports the findings presented here. In §B5 in the appendix, we present the result for employment status (another margin for labor market status), and we find that fluoride has a positive effect.

Table 5: Log Annual Labor Income