“‘Reports of My Death Were Greatly Exaggerated’: Behavior Genetics in the Postgenomic Era”, 2020-09-08 ():
Behavior genetics studies how genetic differences among people contribute to differences in their psychology and behavior.
Here, I describe how the conclusions and methods of behavior genetics have evolved in the postgenomic era in which the human genome can be directly measured. First, I revisit the first law of behavioral genetics stating that everything is heritable, and I describe results from large-scale meta-analyses of twin data and new methods for estimating heritability using measured DNA.
Second, I describe new methods in statistical genetics, including genome-wide association studies and polygenic score analyses.
Third, I describe the next generation of work on gene × environment interaction, with a particular focus on how genetic influences vary across sociopolitical contexts and exogenous environments.
Genomic technology has ushered in a golden age of new tools to address enduring questions about how genes and environments combine to create unique human lives.