“Transgenic Metarhizium Rapidly Kills Mosquitoes in a Malaria-Endemic Region of Burkina Faso”, Brian Lovett, Etienne Bilgo, Souro Abel Millogo, Abel Kader Ouattarra, Issiaka Sare, Edounou Jacques Gnambani, Roch K. Dabire, Abdoulaye Diabate, Raymond J. St. Leger2019 (gene editing)⁠:

Targeting mosquitoes to target malaria: Anopheline mosquitoes transmit the malaria parasite, but the insects themselves are prone to their own infections.

Lovett et al. engineered a specific fungal pathogen of anophelines to carry insect-selective toxins.

The effectiveness of this fungus for controlling mosquitoes was trialed in near-field conditions in Burkina Faso in a setup called MosquitoSphere.

~75% of wild insecticide-resistant mosquitoes released into the environment became infected with the transgenic fungus, causing population collapse within 45 days.