“Long-Term Follow up of the Effect of a Pheromone Therapy on Feline Spraying Behavior”, 2000-12-01 ():
Long-term follow up of 43 cats originally studied in 1997, examining the efficacy of F3 (feline facial pheromone; Feliway), without behavior therapy, on chronic urine spraying problems.
Urine spraying was reduced in 91% of cases during the first 4 weeks of treatment.
A telephone interview was conducted with owners ~10 months after completion of the original trial. 6 cats were still not spraying at this time; in the remaining 37 cats, 27 were still spraying at a lower rate than they had at the start of the trial, 7 were still spraying at the same rate and 3 had deteriorated.
21 owners had not used the treatment in the previous 7 months and 13 owners were still using the pheromone treatment in the home. None were using it on a daily basis. 9 owners used it only when the cat sprayed and 4 on an occasional basis 1–3× a week. 11 owners reported that urine spraying had increased slightly 1–2 months after they stopped using the spray and a further 10 reported a similar change some time later than this. None of the 3 owners whose cats were spraying more than at the start of the trial, and 5 of the 7 who reported no change in spraying frequency had continued to use the pheromone spray, the other 2 were using it on an occasional basis.
It is concluded that treatment with F3 analogue spray results in a long-term change in spraying behavior in some cats.