so last night i grabbed 8 moda’s of various generic brands manufactured in india from one of the indian vendors (all indian brands). extracted modafinil pretty easily with dichloromethane (thanks internet for telling me this was a good solvent and simple process). could tell that the yield was wayy less than 1600mg but didn’t measure it. recrystalized in methanol as that’s the one most patents seem to favor and maybe i was hoping for that polymorphism? idk. i just like crystals. yield: 100mg on the dot.
i’ll be extremely generous and say that before recrystalization the yield could’ve been 3 times that. shit, let’s say it was 5 times that. even then, these pills contained less than 1/3 of the active ingredient that they are reported to contain.
people been knowing this shit is happening forever. the only extraction anybody ever did on reddit at least was water (and he was quite meticulous about it - i actually carried out the same experiment years ago and had similar findings)
so i guess my question is….
what, the, actual, fuck
i would also like to nip a potential bad look in the bud and say that i have nothing but love for my indian brothers & sisters, this is about some shady dudes ripping people off. the indian moda stain is not a stain on india.
edit: prior to this experiment i had done 2 others: a basic cold water extraction (moda is almost completely insoluble in water) and an acid-base extraction manipulating PH values, and in each one yielded much less than half the amount of modafinil claimed on the pill packets.
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