Late 20s woman here. I've recently gone from BMI 30 down to 27 (and still losing) on semaglutide. The main benefit has been psychiatric more than strictly about physical hunger.

I absolutely would have tried it when I was younger if it had been available. I have struggled with food noise and overeating my entire life, hovering around 26/27 with occasional dips below 25 throughout childhood, adolescence, and college.

The fact that I was "only" BMI 26/27 is irrelevant to how overwhelming my cravings always felt.

In the mid-2010s when I was in college, I read a post from The Oatmeal webcomic that personifies this feeling as the Blerch monster. The Blerch is an ugly little gremlin that floats over your shoulder and makes you want to eat All The Things.

When I read that, my heart sank over how relatable all of it was. I was devastated that I was going to have to white-knuckle my Blerch forever. Then I ate all my feelings during covid and ballooned up to BMI 30.

As soon as I tried semaglutide... no more Blerch. Like magic. All the struggling, all the white knuckling, all the inability to stop at just one scoop of ice cream - gone. I can have a small treat and feel satisfied now. I can buy a box of sugary cereal and it will still be there the next day. Last month I bought a jar of Nutella and then forgot it was in my pantry. This is a miracle.

I don't doubt for a second that there are vast swaths of people like me who have struggled with constant food noise at a BMI of "only" ~25/26/27. This kind of mental anguish is constant, no matter how strictly someone has managed to keep the weight down via close calorie tracking and abstaining from all junk food. All that effort is what keeps them from becoming BMI 30+, but they're still sick. They could still benefit from treatment.