Silk Road forums

Discussion => Drug safety => Topic started by: wretched on July 05, 2012, 03:51 am

Title: 4-aco cross tolerance with LSD
Post by: wretched on July 05, 2012, 03:51 am
I would normally use the search bar before posting this, but can anyone give me an idea if 4-aco useage today will effect tolerance to LSD on Friday? I have a VERY important trip to experience on Friday, but a limited supply of sweet Lucy, and if there is cross tolerance, I hope I can adjust to make it as awesome as it deserves to me. The date is set in stone, and I can not not be a part of it.
Title: Re: 4-aco cross tolerance with LSD
Post by: modest mouse on July 05, 2012, 04:04 pm
you mean today and tomorrow?

psychedelics are going to have cross-tolerance issues because they all are affecting the 5HT-2A receptor which produces the characteristic trippy effect...  in the most simple terms. also 1A and 2C, plus with lsd its much more complex with some activity at a few other serotonergic receptors as well as effects on dopaminergic, and adrenergic signaling - which is only effected by 4-aco in very high doses if its like psilocin

it takes a decent break, im not sure exactly but more than a few days to reduce the tolerance. if you want the lsd trip to be the best it can, then id definitely say not to trip right before on 4-aco...
Title: Re: 4-aco cross tolerance with LSD
Post by: rainbowmembrane on July 05, 2012, 09:18 pm
I think you're gonna have to increase the dose buddy.  How many tabs were you planning on taking?  I would say double it to be safe.  The best way to do that, IMO, would be to take half the entire dose...and then as soon as you really start coming up (but no more than 1 1/2 hours after dosing) take the rest.

Graduating doses is a great way to trip.  I used to start with a half tab, then take a full tab about 30 mins in, then take two 30 later...and depending on where I was trying to get, another 2.....or even 4 if the time is right, but that is a seriously heavy trip.

Do you mind if I inquire as to what your unmissable experience is?  Don't need to give details but, camping trip, festival, spiritual journey with a loved one?
Title: Re: 4-aco cross tolerance with LSD
Post by: wretched on July 05, 2012, 10:55 pm
a goodbye party for a friend. I knew it was coming, so I should have planned for it and NOT went balls out on 4-aco for the 4th, but what are you gonna do? I'll figure it out.
Title: Re: 4-aco cross tolerance with LSD
Post by: wretched on July 06, 2012, 03:01 am
all of the good. none of the bad (some stomach discomforting at the max of time warp( shorter but faster hits fast and drifts down/ other waythen shroomsing does. can be weekday light trip or haliday wekend balls out. four eyed monsters on the TV means it is good. before i am liking just like i like lucy if fact, not the deepth but the colors and hearing distortion. I  very much love to watch the trains on 4-aco better than trains on LSD. the trains seem to be a brute force on acid, but on aco, they are singing a song as they float along. I was late on my dose of the party. coming on hard now, and the emotion is overcoming me again. for a moment if you please forget what you believe and maybe you will see that we are all the same.
Title: Re: 4-aco cross tolerance with LSD
Post by: rainbowmembrane on July 06, 2012, 11:28 am
So, how do you dose 4-aco...do you snort it or take it orally?  I've only recently learned about 4-aco and I'm super interested.  I see someone selling 4-aco pills on the shroom listing, I want to try.

How much LSD are you going to take for the party?
Title: Re: 4-aco cross tolerance with LSD
Post by: Limetless on July 06, 2012, 12:30 pm
They are both of the Tryptamine class so it is possible that there would be a cross tolerance but I doubt if there was it would be of any significance.
Title: Re: 4-aco cross tolerance with LSD
Post by: wretched on July 06, 2012, 02:55 pm
it definitely did affect my tolerance, so the stops were pulled out last night. I ended up taking my last 2 tabs of alex grey print 'cid, followed about 30 min later with 20mg of 4-aco-det. the 4-aco was just getting in gear when I started posting last night. about an hour in I iced the cake with a medium sized rail of methylone (that didn't really bring me too much higher) It was a wonderful party, and I felt the connections I was needing. it is hard to say goodbye, and the sadness is still here this morning. Time to take an intermission from psychedelics for a bit.
Title: Re: 4-aco cross tolerance with LSD
Post by: rainbowmembrane on July 06, 2012, 11:51 pm
jeez buddy, that's a lot of mixing!  personally, i'm more of a purist

Title: Re: 4-aco cross tolerance with LSD
Post by: Trinitron421 on July 07, 2012, 12:55 am
They are both of the Tryptamine class so it is possible that there would be a cross tolerance but I doubt if there was it would be of any significance.

LSD may have a tryptamine structure, but I believe it is actually a lysergamide.