Silk Road forums
Discussion => Drug safety => Topic started by: gravitysrainbow on March 06, 2012, 09:16 am
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I heard it was the bees knees but I'd rather make sure it's legit before I fuck myself for good. I've only heard of one guy doing it and he said to mix 25mg of freebase with water and a couple drops of distilled vinegar or lemon juice. I don't want to try this based on this-one-guy I've never met before... so any experience with iv-ing dmt or any advice with iv-ing in general that you might think might be relevant is appreciated.
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Thats pretty much standard procedure for IV, with the exception of you start tripping your balls off before the needle is out of your arm, so an experienced sitter administering the dosage is probably required. i would head over to drug safety for some advice though if you dont know what youre doing.
in order to convert to the salt, preferably you use the dose and the molecular weight to determine the moles of dmt, then use the same moles of acid to fully convert all the freebase to a water soluble form, without overly acidifying the solution. blood is an amazing buffer however, so this may not be an issue give the way people IV acidified heroin
also, there was a clinical study done involving IV doses of DMT in human volunteers by Dr. Strassman, it is an excellent read and highly recommended before you consider such a profound and intense experience.
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If you've just bought some DMT from somewhere and think you can put it up your arm, please DON'T!!!
1) You're going to want to recrystallize the hell outta that DMT, to the point where it is completely white/clear and totally crystalline, before you even think of IVing it... The purity is a serious issue, several recrystallization with hexane should be preformed until the product appears virtual free of any impurities (check by melting point and TLC if possible or burn a small amount and look for a clean burn with no residues).
2) You're probably going to want to use the Fumarate (salt) which is soluble in water, instead of the freebase...
Check out Strassman's studies with IV DMT injection. It is reported that the effects get pretty intense rather fast (depending on dose of course). The high dose in his study was .4mg/kg. So for a 160 pound man a dose of about 29 mg was used. This created almost overwhelming effects with complete disconnection with the ongoing reality with the entrance into the "alien" landscapes of the mind (or whatever one believes). Half this amount .2mg/kg would still produce very intense significant effects, and I would suggest starting LOW and working up!
Also, one would definitely not want to inject oneself as the rapid effects may impede the ability to withdraw the needle causing damage. Thus have a friend who knows what they are doing such as a doctor or vet do the dirty work
This thread (clearnet) has some really helpful and important info: https://mycotopia.net/forums/dmt-spice/19925-dmt-hcl-i-v-expirements-uh-whoa.html
In any case, be sure to do your research before jumping in and BE SAFE!
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If you've just bought some DMT from somewhere and think you can put it up your arm, please DON'T!!!
1) You're going to want to recrystallize the hell outta that DMT, to the point where it is completely white/clear and totally crystalline, before you even think of IVing it... The purity is a serious issue, several recrystallization with hexane should be preformed until the product appears virtual free of any impurities (check by melting point and TLC if possible or burn a small amount and look for a clean burn with no residues).
2) You're probably going to want to use the Fumarate (salt) which is soluble in water, instead of the freebase...
Check out Strassman's studies with IV DMT injection. It is reported that the effects get pretty intense rather fast (depending on dose of course). The high dose in his study was .4mg/kg. So for a 160 pound man a dose of about 29 mg was used. This created almost overwhelming effects with complete disconnection with the ongoing reality with the entrance into the "alien" landscapes of the mind (or whatever one believes). Half this amount .2mg/kg would still produce very intense significant effects, and I would suggest starting LOW and working up!
Also, one would definitely not want to inject oneself as the rapid effects may impede the ability to withdraw the needle causing damage. Thus have a friend who knows what they are doing such as a doctor or vet do the dirty work
This thread (clearnet) has some really helpful and important info: https://mycotopia.net/forums/dmt-spice/19925-dmt-hcl-i-v-expirements-uh-whoa.html
In any case, be sure to do your research before jumping in and BE SAFE!
^THIS!
Be smart, be sane, be safe.
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If you've just bought some DMT from somewhere and think you can put it up your arm, please DON'T!!!
1) You're going to want to recrystallize the hell outta that DMT, to the point where it is completely white/clear and totally crystalline, before you even think of IVing it... The purity is a serious issue, several recrystallization with hexane should be preformed until the product appears virtual free of any impurities (check by melting point and TLC if possible or burn a small amount and look for a clean burn with no residues).
2) You're probably going to want to use the Fumarate (salt) which is soluble in water, instead of the freebase...
Check out Strassman's studies with IV DMT injection. It is reported that the effects get pretty intense rather fast (depending on dose of course). The high dose in his study was .4mg/kg. So for a 160 pound man a dose of about 29 mg was used. This created almost overwhelming effects with complete disconnection with the ongoing reality with the entrance into the "alien" landscapes of the mind (or whatever one believes). Half this amount .2mg/kg would still produce very intense significant effects, and I would suggest starting LOW and working up!
Also, one would definitely not want to inject oneself as the rapid effects may impede the ability to withdraw the needle causing damage. Thus have a friend who knows what they are doing such as a doctor or vet do the dirty work
This thread (clearnet) has some really helpful and important info: https://mycotopia.net/forums/dmt-spice/19925-dmt-hcl-i-v-expirements-uh-whoa.html
In any case, be sure to do your research before jumping in and BE SAFE!
Tagore knows more than I do, so I'd listen to him. ;) I can't even begin to imagine how far out that trip would be though, good luck and if you decide to do this I hope you come back intact. :)
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I forgot to mention Dr Strassmans book is called "DMT: the Spirit Molecule"
Tagore, its not just the fumarate that is soluble in water, it can be converted to other salts as well depending on which acid is readily available. generally it is vinegar, lemon, muriatic... so you get acetate, citrate, or hydrochloride which have different solubilities but I would think theyd be sufficient to get into a warm solution for IV
gravitysrainbow is you name a klaxon reference?
why do you want to IV in the first place? Honestly it is a ton of extra risk without much reason in my mind... smoking provides an excellent bioavailability and delivers the drug rapidly into the bloodstream and across the blood brain barrier, providing an experience nearly equivalent to intravenous use in intensity and pharmacokinetic profile, yet with an enormous increase in safety. Definitely smoke it first before you poke at least. DMT is a beast
Be safe
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Tagore, its not just the fumarate that is soluble in water, it can be converted to other salts as well depending on which acid is readily available. generally it is vinegar, lemon, muriatic... so you get acetate, citrate, or hydrochloride which have different solubilities but I would think theyd be sufficient to get into a warm solution for IV
Yes, probably any of the above salts would be theoretically suitable, but I have only heard of reports using either the fumarate or the hydrochloride. If I were personally dosing I would choose the fumarate over any of the others. Converting to the fumarate salt is both easy and gives theoretically controlled yields and a very clean and safe product which is HIGHLY soluble. AFAIK, this is the salt Strassman used in his studies as well.
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why do you want to IV in the first place? Honestly it is a ton of extra risk without much reason in my mind... smoking provides an excellent bioavailability and delivers the drug rapidly into the bloodstream and across the blood brain barrier, providing an experience nearly equivalent to intravenous use in intensity and pharmacokinetic profile, yet with an enormous increase in safety. Definitely smoke it first before you poke at least. DMT is a beast
This is what I was thinking. The only major benefit I can think of to IV would be conservation of product.
If you do choose to do this, please heed the others' advice: this is not the time to stick yourself. Have a sitter experienced in both IV work and psychedelics, else you may fall out of your head too quickly to keep from plunging the needle in deep.
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If you do choose to do this, please heed the others' advice: this is not the time to stick yourself.
This makes me a curious shredmod - what IS the time to stick yourself? :)
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This makes me a curious shredmod - what IS the time to stick yourself? :)
Well, my answer for my body is "never." I'm not inclined to ever inject myself with anything (hope I'm never diabetic!). However, if you're ever going to shove chunks of metal through your skin and into a vein to become intoxicated, it seems like you shouldn't choose a chemical that will make you almost immediately unaware that you even have a body, much less that it can be damaged. If you want metal-shoving done in this way, let someone else's competent hands do it.
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This makes me a curious shredmod - what IS the time to stick yourself? :)
Well, my answer for my body is "never." I'm not inclined to ever inject myself with anything (hope I'm never diabetic!). However, if you're ever going to shove chunks of metal through your skin and into a vein to become intoxicated, it seems like you shouldn't choose a chemical that will make you almost immediately unaware that you even have a body, much less that it can be damaged. If you want metal-shoving done in this way, let someone else's competent hands do it.
This made me think of a joke from The Hangover II - "Alan, that's supposed to be done by a registered nurse!" "//holds up needle// I am a nurse. I'm just not registered!"
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This makes me a curious shredmod - what IS the time to stick yourself? :)
Well, my answer for my body is "never." I'm not inclined to ever inject myself with anything (hope I'm never diabetic!). However, if you're ever going to shove chunks of metal through your skin and into a vein to become intoxicated, it seems like you shouldn't choose a chemical that will make you almost immediately unaware that you even have a body, much less that it can be damaged. If you want metal-shoving done in this way, let someone else's competent hands do it.
So eloquently put, and sums it up perfectly.
Can't say though that if I had had a chance to participate in Strassman's studies I wouldn't have gone for it though.
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why do you want to IV in the first place? Honestly it is a ton of extra risk without much reason in my mind... smoking provides an excellent bioavailability and delivers the drug rapidly into the bloodstream and across the blood brain barrier, providing an experience nearly equivalent to intravenous use in intensity and pharmacokinetic profile, yet with an enormous increase in safety. Definitely smoke it first before you poke at least. DMT is a beast
This is what I was thinking. The only major benefit I can think of to IV would be conservation of product.
If you do choose to do this, please heed the others' advice: this is not the time to stick yourself. Have a sitter experienced in both IV work and psychedelics, else you may fall out of your head too quickly to keep from plunging the needle in deep.
If the only benefit of IV-ing that you can think of is to conserve product, you've obviously never shot up.
I would definitely have someone injecting me and making sure I don't collapse and hurt myself with the needle.
kinda more interested in getting advice from people who've injected hard drugs, such as ketamine, pcp or cocaine.
I forgot to mention Dr Strassmans book is called "DMT: the Spirit Molecule"
Tagore, its not just the fumarate that is soluble in water, it can be converted to other salts as well depending on which acid is readily available. generally it is vinegar, lemon, muriatic... so you get acetate, citrate, or hydrochloride which have different solubilities but I would think theyd be sufficient to get into a warm solution for IV
gravitysrainbow is you name a klaxon reference?
why do you want to IV in the first place? Honestly it is a ton of extra risk without much reason in my mind... smoking provides an excellent bioavailability and delivers the drug rapidly into the bloodstream and across the blood brain barrier, providing an experience nearly equivalent to intravenous use in intensity and pharmacokinetic profile, yet with an enormous increase in safety. Definitely smoke it first before you poke at least. DMT is a beast
Be safe
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Gravity's Rainbow is a novel written by the father of postmodern fiction, Thomas Pynchon.
injecting drugs isn't very risky if you know what you're doing. people who permanently damage their veins don't know how to test where their valves are, and they're the people who are addicted to a drug they shoot up every day. there's a lot of stigma and bs about doing drugs (pcp makes you go crazy!) and a lot of the drug community even believes this shit because it gives them something to look at and say "well, I may take drugs, but ttthhhaaatttt's not me."
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I forgot to mention Dr Strassmans book is called "DMT: the Spirit Molecule"
If you don't have time to read the book, watch the documentary of the same name! Fascinating stuff.
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Question: I have heard that smoking DMT produces a foul smelling plastic odor that can be quite strong, does this not have the potential to skew your trip in a negative way?
I've never tried DMT, a shame since I live a couple of hours from amazonian jungle where I could legally try ayahuasca, but I have read The Spirit Molecule and would highly recommend it to anyone with interest in the soul and/or psychedelics.
I really can't stand needles and I'm unlikely to be able to get hold of smokable dmt so I will at best get to try drinking it with maois one day.
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If the only benefit of IV-ing that you can think of is to conserve product, you've obviously never shot up.
I would definitely have someone injecting me and making sure I don't collapse and hurt myself with the needle.
Sorry, I should have been clearer: I meant it's the only (major) benefit I could think of for IV of DMT specifically. Obviously there are minor benefits, such as precise dosage control and perhaps a slightly faster comeup (which is not a benefit to me, since DMT is already so fast). Since, as microRNA mentioned, the effects should be nearly identical due to DMT's bioavailability, I stand by my statement that the only MAJOR benefit is conservation, which is admittedly nice, since you can just about half your dose for the same experience. What big benefit am I missing that you consider worthwhile?
Since you're already aware of the safety issues, and will have those bases covered, so I say go for it if you want!
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Question: I have heard that smoking DMT produces a foul smelling plastic odor that can be quite strong, does this not have the potential to skew your trip in a negative way?
I've never tried DMT, a shame since I live a couple of hours from amazonian jungle where I could legally try ayahuasca, but I have read The Spirit Molecule and would highly recommend it to anyone with interest in the soul and/or psychedelics.
I really can't stand needles and I'm unlikely to be able to get hold of smokable dmt so I will at best get to try drinking it with maois one day.
The smell and taste can definitely get to some people. I have a friend who struggles to take a hit of DMT just due to the taste. However, I don't believe it would alter the trip just an uncomfortable time dosing. Personally, after returning from a breakthrough I find the smell to remind very relaxing. I've probably just associated the taste and smell with my DMT trips which are pure bliss.
To the OP, I hope you report back on your experience! Smoking DMT is already very intense so I would love to hear a personal report on an IV dose. Best of luck!
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Question: I have heard that smoking DMT produces a foul smelling plastic odor that can be quite strong, does this not have the potential to skew your trip in a negative way?
I've never tried DMT, a shame since I live a couple of hours from amazonian jungle where I could legally try ayahuasca, but I have read The Spirit Molecule and would highly recommend it to anyone with interest in the soul and/or psychedelics.
I really can't stand needles and I'm unlikely to be able to get hold of smokable dmt so I will at best get to try drinking it with maois one day.
If you vaporize it properly the smell won't be there. As far as ruining your trip, ime natural taste will be a completely foreign concept to you and will have no effect on your trip.
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I wouldn't IV it unless it was synthesized by a professional in a lab. Not shit that's been extracted from plants. I know purification is the same either way, but I wouldn't trust that the hexane is ONLY pulling DMT. You don't know what else was in the plant material, what it was extracted with or what it has come into contact with.