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Simvastatin is used together with diet, weight-loss, and exercise to reduce the amount
of fatty substances such as low-density lipoprotein (LDL) cholesterol ('bad cholesterol')
and triglycerides in the blood and to increase the amount of high-density lipoprotein (HDL)
cholesterol ('good cholesterol') in the blood. Simvastatin may also be used to decrease the
amount of cholesterol and other fatty substances in the blood in children and teenagers 10
to 17 years of age who have familial heterozygous hypercholesterolemia (an inherited condition
in which cholesterol cannot be removed from the body normally). Simvastatin is also used to decrease
the risk of heart attacks, strokes, and death, and to decrease the need for surgery to improve blood
flow in people who have medical conditions that put them at high risk of developing heart and blood
vessel problems. Simvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins).
It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that
may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.
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