Gabapentin 20 x 300mg Sandoz Capsules, Dispensed by UK pharmacy ~ 5 months old -- Ships From United Kingdom

12.51109856 LTC
0.25048481 BTC
$31.00 USD


Preview of available shipping methods:


Item Description:
Gabapentin 20 x 300mg Sandoz Capsules, Dispensed by UK pharmacy.
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

(Alternative to Lyrica, very similar in pain-relieving properties)


Pharmacodynamics
------------------------
Gabapentin, an analog of GABA, is used as an anticonvulsant to treat partial seizures, amyotrophic lateral sclerosis (ALS), and painful neuropathies. Potential uses include monotherapy of refractory partial seizure disorders, and treatment of spasticity in multiple sclerosis, tremor. mood disorders, and attenuation of disruptive behaviors in dementia. Gabapentin has high lipid solubility, is not metabolized by the liver, has no protein binding, and doesn't possess the usual drug interactions.

Mechanism / Action
-------------------------
Gabapentin interacts with cortical neurons at auxillary subunits of voltage-sensitive calcium channels. Gabapentin increases the synaptic concentration of GABA, enhances GABA responses at non-synaptic sites in neuronal tissues, and reduces the release of mono-amine neurotransmitters. One of the mechanisms implicated in this effect of gabapentin is the reduction of the axon excitability measured as an amplitude change of the presynaptic fibre volley (FV) in the CA1 area of the hippocampus. This is mediated through its binding to presynaptic NMDA receptors. Other studies have shown that the antihyperalgesic and antiallodynic effects of gabapentin are mediated by the descending noradrenergic system, resulting in the activation of spinal alpha2-adrenergic receptors. Gabapentin has also been shown to bind and activate the adenosine A1 receptor.

Absorption
--------------
Rapid. Absorbed in part by the L-amino acid transport system, which is a carrier-mediated, saturable transport system; as the dose increases, bioavailability decreases. Bioavailability ranges from approximately 60% for a 900 mg dose per day to approximately 27% for a 4800 milligram dose per day. Food has a slight effect on the rate and extent of absorption of gabapentin (14% increase in AUC).


------------------------------------------------------------------------------------------------------------------

SHIPPING
~~~~~~~~

* All orders are dispatched the same or next day (except Sundays).

* Domestic orders sent Royal Mail First Class. Royal Mail aims to deliver First Class UK mail next day.
* International orders sent Royal Mail Airmail. Delivery times vary per country, but 3 days is typical within EU, and 4/5 days outside EU.

* All packages are professionally packaged with a vacuum seal. We take security and stealth very seriously.

------------------------------------------------------------------------------------------------------------------

FINALISING + PAYMENT
~~~~~~~~~~~~~~~~~~~

* We do not ask for finalising early.

* Please finalise within 24 hours of receipt of your order.

* Payment in Litecoins preferred, but Bitcoins are accepted without problem.

* We reserve the right to cancel an order at our discretion based on: buyer stats, malicious feedback, failure to finalise after an order has been received, or failure to leave feedback.

------------------------------------------------------------------------------------------------------------------

FEEDBACK
~~~~~~~~~~

* Please leave feedback, Deepweb marketplaces depend on this.

* We aim for 5/5 feedback ratings. In the unlikely event, you feel service has been substandard for whatever reason, please contact and give us the chance to resolve the issue.

------------------------------------------------------------------------------------------------------------------

CONTACT
~~~~~~~~

* If the Atlantis website is unavailable:

Tormail – nextdayuk@tormail.org
Hushmail - nextdayuk@hush.com


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~


This item has no feedback yet.