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U47700 - Synthetisches Heroin 5gr < 98% Purity synthetic opioid
5gr U47700 (very potent) you need to be careful similar to those of other potent opioid agonists, including strong analgesia, sedation, euphoria 7,5 x analgetische Potenz von Morphium. U-47700 has a full IUPAC name of trans-3,4-dichloro-N-(2-(dimethylamino)cyclohexyl)-N-methylbenzamide which belongs to a class of synthetic opioid research chemicals. -bitte nur bestellen wenn ihr mit solche...
Sold by Leckerland - 0 sold since Jun 11, 2016 Vendor Level 2 Trust Level 3
Product Description
5gr U47700 (very potent) you need to be careful
similar to those of other potent opioid agonists, including strong analgesia, sedation, euphoria
7,5 x analgetische Potenz von Morphium.
U-47700 has a full IUPAC name of trans-3,4-dichloro-N-(2-(dimethylamino)cyclohexyl)-N-methylbenzamide which belongs to a class of synthetic opioid research chemicals.
-bitte nur bestellen wenn ihr mit solchen gefährlich reinen und hochpotenten Substanzen umgehen könnt!
-Lebensgefahr!
U-47700 has never been studied in humans, but would be expected to produce effects similar to those of other potent opioid agonists, including strong analgesia, sedation, euphoria, constipation, itching and respiratory depression which could be harmful or fatal. Tolerance and dependence would be expected to develop.
Combined consumption of U-47700 and fentanyl caused one fatality in Belgium.[19][20] 17 opioid overdoses and several deaths in the USA had initially been connected to U-47700 in April 2016,[21] as of June 2016 at least 50 deaths were confirmed.[22]
Legal status
U-47700 is an opioid analgesic drug developed by a team at Upjohn in the 1970s.[2] U-47700 was derived from an earlier opioid AH-7921. U-47700 is selective for the µ-opioid receptor with a Kd value of 5.3 nM compared to 910 nM for the κ-opioid receptor[3][4] and has around 7.5 x the potency of morphine in animal models.[5][6]
U-47700 is the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. The team looked for the key moieties which gave the greatest activity.[7] Upjohn posted over a dozen patents on related compounds, each optimizing one moiety] until they discovered that U-47700 was the most active.
Legal status
Illegal in Finland, Sweden, Ohio
U-47700 became the lead compound of selective kappa-opioid receptor ligands such as U-50488 (containing a single methylene spacer difference) and U-69,593, which share very similar structures.[3] Its structure led to other chemists experimenting with it to see if rigid analogues would retain activity.[16] Although not used medically, the selective kappa ligands are used in research
• One sealed aluminum foil bag containing highest gradetrans-3,4-dichloro-N-(2-(dimethylamino)cyclohexyl)-N-methylbenzamide opioid research chemical
• A crystalline solid
• 98% Purity