Question for knowledgeable CBD users

I have a good friend who's been taking care of me and while CBD strains such as Harlequin and others are probably most ideal to use would you say CBD tenure, capsules and CBD cartridges are the next best options? I'm assuming CBD strains are the most effective regardless and the reason I ask this question is because I have no experience with any other CBDs alternatives.


Comments


[2 Points] SethProff:

Cbd will keep you calm, it's sometimes a bit rough I think, not as good as marijuana in my opinion


[1 Points] None:

Entourage effect- to get the best medical effect, smoke high cbd strains or cbd distillate with a significant amount of THC still present. dabbing pure cbd crystal mixed with normal cannabis extracts would probably be the most effective.


[1 Points] bird-biotic:

I live in a legal state and have experimented with a bunch of CBD strains on offer. Not really a huge pot person in general just was looking for epilepsy and anxiety. TMI I did some research on this last week for something unrelated. have more links if you want. peace.

Anyway, Interesting question. This is such a rapidly expanding market there seems to be quite a few funded research studies regarding bioavailabiliity of CBD for medicinal use. 'bioavailability + CBD" or "pharmikonetics + CBD" in google or google scholar/books will pop up a few interesting things. scrolling to the concluding paragraph saves time from the pedantic bullshit.

That said,

"The topic of cannabinoid absorption is well understood and has been repeatedly studied. Bioavailability of CBD (or of THC) varies greatly by delivery method. Smoking typically delivers cannabinoids at an average bioavailability rate of 30%2. Cannabinoids that are absorbed through the mucous membranes in the mouth (buccal mucosal application) have bioavailabilities of around 13%3. By comparison, orally consumed cannabis edibles typically deliver cannabinoids at an average bioavailability rate of only 5%4 " From Cannabis Health Journal - contributors are all MD's, info looks legit https://cannabishealth.com/bioavailability-of-cannabinoids-via-ingestion-developing-an-advanced-delivery-model/

Here's some other kinda interesting info: It's anecdotal evidence from Medical marijuana patients in California. title is Old Hippie's Guide to CBD"

http://beyondchronic.com/2010/12/old-hippie-definitive-guide-cbd-medical-marijuana/ "How To Get More CBD According to a well-known NorCal expert named Baker Buck, the leaves of a plant have more CBD than the buds. I’ve made tinctures and capsules with leaves alone, but also from stems, branches, and even roots. These tend to give a much stronger body effect than is typical from random strains. You can get the same effect by using stems and leaves, rather than bud, for cooking or making QWISO hash.

But wait, there’s more. It turns out that Dr. William Courtney (a so-called “pot doctor” who actually does serious research on the matter) recommends eating raw leaves to many people for medical reasons. He also talks about juicing the leaves (use one of these) to get the essence without the stomach upsets that can come from the leaves themselves. And of course, eating or juicing marijuana, or carefully cooking with it, will guarantee that you get virtually complete availability of all the important compounds in it. Heck…smoking it is going to burn out half the good stuff at random…it’s about the worst way to consume it there is!

And that brings us to the third way of increasing your CBD intake. If you have a vaporizer with a digital temperature readout, you can actually decide to “boil off” the THC and leave the CBD alone¹. THC will begin to boil and vaporize at only 150° to 157°C (302° to 315°F), while CBD waits until somewhere around 160° to 188°C (depending on who you believe), which corresponds to 320° to 370°F. So if you set your vaporizer to 160°C/320°F, your THC will be vaporizing…you can inhale it or wait for it to dissipate. After the cannabis changes color to brown, you can crank up the temperature setting above 188°C/370°F and now inhale the CBD, with far less of a “high”. You’re essENTially now performing fractional distillation…it’s the same way they make fine brandy…and gasoline!

This is great in theory, but in practice it will not be effective with most strains, because virtually all cannabis available, even in dispensaries, has 1% CBD or less (usually a lot less). So, unless you’re experimenting with an actual high CBD strain, you’ll just end up burning off a lot of THC and end up with nothing much at the end, unless you use a larger amount of cannabis than usually necessary. Deliberately using AVB in tinctures, edibles, or capsules will easily demonstrate this effect without wasting anything, since AVB already has had much of the THC removed, and you’re recycling it anyway!

Marijuana generally comes in two basic types: Indica and Sativa. Sativas tend to have a higher THC:CBD ratio, and indicas generally have more CBD than sativas, though again both types usually have less than 1% CBD in any case. It’s the “other” components: the terpenes, terpenoids, and minor cannabinoids (0.1% or less) that influence the type of high you get, in combination with the CBD:THC ratio. All this combines to make sativas more likely to cause anxiety or paranoia, whereas indicas are usually used to treat anxiety or paranoia! But dosage plays a big part in this as well; keep the dosage down, and you’re less likely to have a bad time.

This adverse side effect of anxiety comes from THC, and that’s most evident when looking at Marinol, the only form of “medical marijuana” sanctioned by the Federal government at this time for prescription use. I put “medical marijuana” in scare quotes there because Marinol is not even made from cannabis; it’s pure synthesized THC (in sesame oil caplets). And, because it’s not moderated by CBD (as it would be in the natural plant), Marinol often causes users severe anxiety or worse: at least four people have died from using it.

But many of the high CBD strains around, for whatever horticultural reason, are actually sativas. Harlequin, which is generally available at SPARC, is 6.5% THC and 8.5% CBD. I’ve also gotten some Omrita RX3, which (according to Abby on the MassSpec) is just 5.5% THC and an astounding 10% CBD. It usually takes two hits of cannabis on my MFLB for me to start feeling any head effects; with Omrita it took 4 hits to feel that (makes perfect sense by the THC percentage). It doesn’t make me feel “numb” at all, but all pain just magically…goes…away.

¹If you use a more basic vaporizer, like I do, you can get the same effect by using your ABV/AVB (the residual weed left over after vaping) for cooking. It’s had the THC removed already." http://beyondchronic.com/2010/12/old-hippie-definitive-guide-cbd-medical-marijuana/


[1 Points] justathrowawayaway1:

Does CBD oil show up on probation drug tests?