Post-exposure prophylaxis (PEP) + Recreational drugs?

Hi, Just wondering if anyone had any experience of mixing Ritonavir (Norvir) + Emtricitabine/tenofovir disoproxil + Darunavir and any kind of recreational drug. There is a shit ton of warnings concerning alcohol but nothing concerning the rest. Thanks,


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[3 Points] jtronicustard:

Those drugs are notoriously hard on the liver and kidneys. Any drug that affects systemic circulation may put undue strain on your liver, ie stimulants. Your opiates and downers would likely have fewer deleterious cardiovascular effects, but may stay in your circulation longer bc the liver will be 'preoccupied' processing your PEP.


[1 Points] None:

I took PrEP along with practically every drug class possible. It did not feel extremely healthy along with amphetamines or alcohol. Opiates seemed alright. This is all from my subjective experience though.